N-乙酰基-3-吲哚啉酮合成路线 （共 51 条）
反应条件
in waessriger neutraler oder schwach alkalischer Loesung;
参考文献
DE131400 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 6, p. 554
Chemische Berichte, , vol. 34, p. 1856
Chem. Zentralbl., , vol. 73, # I p. 1343
反应条件
1: 1.) P2O5 / 1.) 5-10 deg C; 2.) DMF, 20 deg C, 15 h 2: 87.5 percent / potassium acetate / ethanol; H2O / 2 h / Heating View Scheme
参考文献
Velezheva, V. S.; Smushkevich, V. Yu.; Romanova, O. B.; Kurkovskaya, L. N.; Suvorov, N. N.
Journal of Organic Chemistry USSR (English Translation), 1986 , vol. 22, # 11 p. 2186 - 2193
Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 11 p. 2434 - 2443
反应条件
1: 35 percent / acetic acid / 1 h / boiling 2: 81 percent / 0.42 h / boiling 3: 75 percent / triethylamine / methanol / 1 h / boiling 4: 31 percent / POCl3 / 20 h / 20 °C View Scheme
参考文献
Ryabova; Tugusheva; Alekseeva; Granik
Pharmaceutical Chemistry Journal, 1996 , vol. 30, # 7 p. 472 - 477
反应条件
hydrogenchloride; water; iron(III) chloride
参考文献
Spencer
Journal of the Society of Chemical Industry, London, 1931 , vol. 50, p. 63 T
参考文献
Chemische Berichte, , vol. 52, p. 328
反应条件
sodium hydride in tetrahydrofuran T=0 - 20°C; Horner-Emmons reaction;
参考文献
Merour, Jean-Yves; Gadonneix, Philippe; Malapel-Andrieu, Beatrice; Desarbre, Eric
Tetrahedron, 2001 , vol. 57, # 10 p. 1995 - 2002
反应条件
triethylamine 1) benzene, a) 1 h, 20 deg C, b) 1 h, reflux, 2) methanol, 30 min, reflux; Yield given. Multistep reaction;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 26, # 11 p. 1238 - 1244
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 26, # 11 p. 1487 - 1494
反应条件
sulfuric acid in acetic anhydride T=20°C; 20 h;
参考文献
Velezheva, V. S.; Smushkevich, V. Yu.; Romanova, O. B.; Kurkovskaya, L. N.; Suvorov, N. N.
Journal of Organic Chemistry USSR (English Translation), 1986 , vol. 22, # 11 p. 2186 - 2193
Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 11 p. 2434 - 2443
反应条件
1: 88.8 percent / conc. H2SO4 / acetic anhydride / 20 h / 20 °C 2: 10percent NaOH / 2 h / 20 °C View Scheme
参考文献
Velezheva, V. S.; Smushkevich, V. Yu.; Romanova, O. B.; Kurkovskaya, L. N.; Suvorov, N. N.
Journal of Organic Chemistry USSR (English Translation), 1986 , vol. 22, # 11 p. 2186 - 2193
Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 11 p. 2434 - 2443
反应条件
kieselguhr; nickel; decalin T=80°C; P=73550.8 Torr; Hydrogenation;
参考文献
I.G. Farbenind.
Patent: DE515544 , 1928 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 17, p. 639
