2-(乙硫基)喹唑啉-4(3H)-酮合成路线 （共 14 条）
反应条件
sodium ethanolate in ethanol T=20°C; 3 h; Heating / reflux;
参考文献
SK CHEMICALS CO., LTD.; LEADGENEX INC.; INDUSTRY ACADEMIC COOPERATION FOUNDATION OF KYUNGHEE UNIVERSITY
Patent: US2008/207614 A1, 2008 ;
Location in patent: Page/Page column 15-16 ;
反应条件
potassium carbonate in neat (no solvent) T=20°C; Green chemistry; SolventTemperatureTimeReagent/catalyst;
参考文献
Reddy, B. Srinivasa; Naidu; Dubey
Asian Journal of Chemistry, 2013 , vol. 25, # 5 p. 2644 - 2646
反应条件
potassium hydroxide in ethanol T=100°C; 3 h;
参考文献
Yun, L. M.; Yangibaev, S.; Shakhidoyatov, Kh. M.; Alekseeva, V. Ya.; V'yunov, K. A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1987 , vol. 23, # 2 p. 214 - 216
Khimiya Geterotsiklicheskikh Soedinenii, 1987 , vol. 23, # 2 p. 254 - 256
反应条件
tetrabutylammomium bromide; potassium carbonate in 1,4-dioxane T=25°C;
参考文献
Khalil
Phosphorus, Sulfur and Silicon and the Related Elements, 2005 , vol. 180, # 11 p. 2533 - 2541
反应条件
1: 56 percent / glacial acetic acid / 2 h / Heating 2: 78 percent / KOH / ethanol / Heating View Scheme
参考文献
Shakhadoyatov, Kh. M.; Yangibaev, S.; Yun, L. M.; Kadyrov, Ch. Sh.
Chemistry of Natural Compounds, 1982 , vol. 18, # 1 p. 106 - 111
Khimiya Prirodnykh Soedinenii, 1982 , vol. 18, # 1 p. 112 - 118
参考文献
Hori; Iemura; Hara; Ozaki; Sukamoto; Ohtaka
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 3 p. 681 - 687
反应条件
1: 81 percent / 155 - 160 °C 2: 88 percent / POCl3 / 130 °C 3: 96 percent / 60percent NaH / dimethylformamide / 60 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 38, # 3 p. 681 - 687
反应条件
1: 81 percent / 155 - 160 °C 2: 88 percent / POCl3 / 130 °C 3: 55 percent / 60percent NaH / dimethylformamide / 60 °C View Scheme
参考文献
Hori; Iemura; Hara; Ozaki; Sukamoto; Ohtaka
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 3 p. 681 - 687
反应条件
1: 81 percent / 155 - 160 °C 2: 88 percent / POCl3 / 130 °C 3: 74 percent / 60percent NaH / dimethylformamide / 60 °C View Scheme
参考文献
Hori; Iemura; Hara; Ozaki; Sukamoto; Ohtaka
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 3 p. 681 - 687
反应条件
1: 84 percent / 155 - 160 °C 2: 50 percent / K2CO3 / ethanol / Heating 3: 94 percent / POCl3 / 130 °C 4: 96 percent / 60percent NaH / dimethylformamide / 60 °C View Scheme
参考文献
Hori; Iemura; Hara; Ozaki; Sukamoto; Ohtaka
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 3 p. 681 - 687
