4-氨基-2,3,5,6-四氟吡啶合成路线 (共 43 条)
反应条件
cesium fluoride; 1,1,1,3,3,3-hexamethyl-disilazane in N,N-dimethyl-formamide T=100°C; 5 h; Yields of byproduct given;
参考文献
Miller, Alexey O.; Furin, Georgii G.
Journal of Fluorine Chemistry, 1995 , vol. 75, # 2 p. 169 - 172
反应条件
potassium carbonate in tetrahydrofuran T=70°C; 3 h;
参考文献
Miller, A.O.; Furin, G. G.
Journal of Fluorine Chemistry, 1987 , vol. 36, p. 247 - 272
反应条件
cesium fluoride in acetonitrile T=20°C; 1 h;
参考文献
European Journal of Inorganic Chemistry, , # 8 p. 2123 - 2134
反应条件
cesium fluoride in acetonitrile T=20°C; 1 h;
参考文献
European Journal of Inorganic Chemistry, , # 8 p. 2123 - 2134
反应条件
ammonium hydroxide in tetrahydrofuran 24 h; Heating;
参考文献
Banks; Besheesh; Tsiliopoulos
Journal of Fluorine Chemistry, 1996 , vol. 81, # 1 p. 39 - 42
反应条件
sodium hydrogencarbonate in acetonitrile T=20°C; 23 h;
参考文献
Cartwright, Matthew W.; Sandford, Graham; Bousbaa, Jamaal; Yufit, Dmitrii S.; Howard, Judith A.K.; Christopher, John A.; Miller, David D.
Tetrahedron, 2007 , vol. 63, # 30 p. 7027 - 7035
反应条件
hydrogen iodide in water reflux, 2 h;;
参考文献
Gmelin Handbook: F: PerFHalOrg.5, 4.1.1.3, page 180 - 219
反应条件
in ethanol; water 110 °C, 8 h;;
参考文献
Banks, R. E.; Burgess, J. E.; Cheng, W. M.; Haszeldine, R. N.
Journal of the Chemical Society, 1965 , p. 575 - 594
Full Text Show Details
Gmelin Handbook: F: PerFHalOrg.5, 4.1.1.3, page 180 - 219
反应条件
sodium disulfite; hydrogen iodide 1 h; Heating;
参考文献
Journal of Fluorine Chemistry, , vol. 40, p. 147 - 170
反应条件
sodium hydride in 1-methyl-pyrrolidin-2-one T=100°C; 20 h;
参考文献
Coe, Paul L.; Rees, Anthony J.; Whittaker, Jane
Journal of Fluorine Chemistry, 2001 , vol. 107, # 1 p. 13 - 22