(S)-(+)-5,5-二甲基-4-苯基-2-恶唑烷酮合成路线 （共 29 条）
反应条件
sodium tetrahydroborate in methanol 0.166667 h;
参考文献
Tetrahedron, , vol. 64, # 39 p. 9320 - 9344
反应条件
sodium tetrahydroborate in methanol T=20°C; 0.166667 h;
参考文献
Davies, Stephen G.; Key, Min-Suk; Rodriguez-Solla, Humberto; Sanganee, Hitesh J.; Savory, Edward D.; Smith, Andrew D.
Synlett, 2003 , # 11 p. 1659 - 1662
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane T=20°C; 12 h;
参考文献
Tetrahedron, , vol. 64, # 39 p. 9320 - 9344
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 1 h;
参考文献
Tetrahedron, , vol. 64, # 39 p. 9320 - 9344
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 1 h;
参考文献
Tetrahedron, , vol. 64, # 39 p. 9320 - 9344
反应条件
(R)-BTM; sodium sulfate; N-ethyl-N,N-diisopropylamine in chloroform T=20°C; 12 h;
参考文献
Journal of the American Chemical Society, , vol. 128, # 20 p. 6536 - 6537
反应条件
diisobutylaluminium hydride in hexane; dichloromethane T=-78°C; 0.333333 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 1, # 16 p. 2886 - 2899
反应条件
trifluorormethanesulfonic acid; methoxybenzene in toluene Birch reduction; 3 h;
参考文献
Sugiyama, Shigeo; Arai, Satoshi; Ishii, Keitaro
Heterocycles, 2005 , vol. 65, # 1 p. 149 - 159
反应条件
1: tetrahydrofuran 2: t-BuONa / tetrahydrofuran 3: i-Pr2NEt; Na2SO4; (R)-BTM / CHCl3 / 12 h / 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 128, # 20 p. 6536 - 6537
反应条件
in dichloromethane 2 h; Inert atmosphereReflux;
参考文献
WO2010/32147 A2, ;
Page/Page column 33-34 ;
WO 2010/032147 A2
