(S)-(+)-5,5-二甲基-4-苯基-2-恶唑烷酮合成路线 （共 29 条）
反应条件
diphenyl phosphoryl azide; triethylamine in toluene T=80°C; 8 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 63, # 8 p. 2742 - 2748
反应条件
sodium tetrahydroborate in methanol 0.166667 h;
参考文献
Tetrahedron, , vol. 64, # 39 p. 9320 - 9344
反应条件
potassium tert-butylate in tetrahydrofuran T=0°C; Yield given;
参考文献
Synlett, , # 5 p. 519 - 521
反应条件
sodium tetrahydroborate in methanol 0.166667 h;
参考文献
Tetrahedron, , vol. 64, # 39 p. 9320 - 9344
反应条件
sodium tetrahydroborate in methanol 0.166667 h;
参考文献
Tetrahedron, , vol. 64, # 39 p. 9320 - 9344
反应条件
1.1: LHMDS / tetrahydrofuran / 0.5 h / 0 °C 1.2: 77 percent / tetrahydrofuran / 5 h / 0 °C 2.1: 26 percent / DIBAL / CH2Cl2; hexane / 0.33 h / -78 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 1, # 16 p. 2886 - 2899
反应条件
1: 84 percent / CHCl3 / 2 h / 0 - 20 °C 2: NaBH4 / methanol / 0.17 h / 20 °C View Scheme
参考文献
Synlett, , # 11 p. 1659 - 1662
反应条件
1.1: p-toluenesulfonic acid monohydrate / toluene / 24 h / Heating 2.1: sodium borohydride; acetic acid / tetrahydrofuran / 0 - 20 °C 2.2: HCl / hexane; dioxane / 4 h / 20 °C 2.3: Et3N / 1,2-dichloro-ethane / 6 h / Heating 3.1: 84 percent / TfOH; anisole / toluene / 3 h View Scheme
参考文献
Heterocycles, , vol. 65, # 1 p. 149 - 159
反应条件
1: 61 percent / CHCl3 / 0 - 20 °C 2: LiAlH4 / tetrahydrofuran / 20 °C View Scheme
参考文献
Synlett, , # 11 p. 1659 - 1662
反应条件
1: 100 percent / CHCl3 / 0 - 20 °C 2: LiAlH4 / tetrahydrofuran / 20 °C View Scheme
参考文献
Synlett, , # 11 p. 1659 - 1662
