(S)-(+)-5,5-二甲基-4-苯基-2-恶唑烷酮合成路线 （共 29 条）
反应条件
1: MCPBA / CHCl3 / 0 - 20 °C 2: NaBH4 / methanol / 0.17 h / 20 °C View Scheme
参考文献
Synlett, , # 11 p. 1659 - 1662
反应条件
1: 60 percent / CHCl3 / 0 - 20 °C 2: NaBH4 / methanol / 0 - 20 °C View Scheme
参考文献
Synlett, , # 11 p. 1659 - 1662
反应条件
1: tetrahydrofuran; diethyl ether / Ambient temperature 2: t-BuOK / tetrahydrofuran / 0 °C View Scheme
参考文献
Synlett, , # 5 p. 519 - 521
反应条件
1.1: p-toulenesulfonic acid monohydrate / toluene / Heating 1.2: 58 percent / sodium borohydride; acetic acid / tetrahydrofuran / 0 - 20 °C 2.1: Et3N / 1,2-dichloro-ethane / 6 h / Heating 3.1: MsOH; anisole / toluene / 1.5 h View Scheme
参考文献
Heterocycles, , vol. 65, # 1 p. 149 - 159
参考文献
Tetrahedron, , vol. 55, # 11 p. 3337 - 3354
反应条件
1: 1) copper bromide dimethylsulfide complex, (CH3)2S / 1) THF, -40 deg C, 10 min, 2) THF, -15 deg C, 30 min 2: 84 percent / 24 h View Scheme
参考文献
Tetrahedron, , vol. 55, # 11 p. 3337 - 3354
参考文献
Tetrahedron: Asymmetry, , vol. 6, # 3 p. 671 - 674
反应条件
Multistep reaction. Title compound not separated from byproducts;
参考文献
Heterocycles, , vol. 65, # 1 p. 149 - 159
反应条件
1: (4S)-5,5-dimethyl-4-phenyl-1,3-oxazolidin-2-one With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.25 h; 2: 3-phenyl-propionyl chloride in tetrahydrofuran; hexane T=-78 - 20°C; Further stages.;
参考文献
Organic and Biomolecular Chemistry, , vol. 1, # 16 p. 2886 - 2899
