(二甲基氨亚甲基)丙二腈合成路线 （共 23 条）
反应条件
1,2-dichloro-ethane in 0-acetylhydroxylamine hydrochloride
反应条件
1: With pyridine; trichlorophosphate T=-10°C; 15 h; Large scale reaction; 2: With sodium hydroxide in water pH=3; Cooling with iceLarge scale reaction;
参考文献
Organic Process Research and Development, , vol. 16, # 1 p. 57 - 60
参考文献
Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, , vol. 295, p. 516 - 523
反应条件
potassium fluoride; N-benzyl-N,N,N-triethylammonium chloride in dichloromethane 6 h; Ambient temperature;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 23, # 12 p. 1176 - 1180
反应条件
in N-methyl-acetamide; dichloromethane; water
反应条件
in tetrahydrofuran; dichloromethane T=20°C; 1 h;
参考文献
Synthetic Communications, , vol. 37, # 3 p. 417 - 423
反应条件
silver trifluoroacetate; triethylamine in acetonitrile 1 h; Ambient temperature;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 67, # 11 p. 3048 - 3052
反应条件
in diethyl ether; toluene
参考文献
Journal of the American Chemical Society, , vol. 97, # 4 p. 800 - 807
反应条件
in toluene T=80°C; 20 h;
参考文献
Liebigs Annalen der Chemie, , # 3 p. 358 - 371
反应条件
1: N,N-dimethylformamide-dimethyl sulfate complex With sodium methylate in methanol T=-5°C; 0.0833333 h; Large scale reaction; 2: malononitrile in methanol T=-5°C; 0.5 h; Large scale reaction;
参考文献
Organic Process Research and Development, , vol. 16, # 1 p. 57 - 60
