(1S,2S)-(+)-2-氨基-1-[4-(甲硫基)苯基-1,3-丙二醇合成路线 （共 6 条）
反应条件
1: triethylamine / CH2Cl2 2: tosyl cloride / CH2Cl2 / 40 °C 3: 90 percent / dimethyl sulphoxyde, oxalyl chloride, triethylamine / CH2Cl2 / -20 °C 4: 90 percent / sodium borohydride / methanol / -20 °C 5: 1NHCl / 20 °C 6: 10percent w/v NaOH / 100 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 29, # 43 p. 5561 - 5564
反应条件
1: 90 percent / sodium borohydride / methanol / -20 °C 2: 1NHCl / 20 °C 3: 10percent w/v NaOH / 100 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 29, # 43 p. 5561 - 5564
反应条件
1: 90 percent / dimethyl sulphoxyde, oxalyl chloride, triethylamine / CH2Cl2 / -20 °C 2: 90 percent / sodium borohydride / methanol / -20 °C 3: 1NHCl / 20 °C 4: 10percent w/v NaOH / 100 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 29, # 43 p. 5561 - 5564
反应条件
1: tosyl cloride / CH2Cl2 / 40 °C 2: 90 percent / dimethyl sulphoxyde, oxalyl chloride, triethylamine / CH2Cl2 / -20 °C 3: 90 percent / sodium borohydride / methanol / -20 °C 4: 1NHCl / 20 °C 5: 10percent w/v NaOH / 100 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 29, # 43 p. 5561 - 5564
反应条件
1: triethylamine / CH2Cl2 2: tosyl cloride / CH2Cl2 / 40 °C 3: 90 percent / dimethyl sulphoxyde, oxalyl chloride, triethylamine / CH2Cl2 / -20 °C 4: 90 percent / sodium borohydride / methanol / -20 °C 5: 1NHCl / 20 °C 6: 10percent w/v NaOH / 100 °C View Scheme
参考文献
Giordano, Claudio; Cavicchioli, Silvia; Levi, Silvio; Villa, Marco
Tetrahedron Letters, 1988 , vol. 29, # 43 p. 5561 - 5564
反应条件
1: 93 percent / K2CO3 / ethane-1,2-diol; glycerol / 20 h / 110 °C
2: 86 percent / Raney-Ni W-2 / aq. ethanol / 9 h / Heating
3: 91 percent / aq. 20percent HCl / 6 h / Heating
View Scheme
参考文献
Rozwadowska, Maria D.
Tetrahedron Asymmetry, 1998 , vol. 9, # 9 p. 1615 - 1618
