2,3-二氯-4-羟基苯甲醛合成路线 （共 6 条）
反应条件
calcium hydroxide powder; sodium carbonate in water 2 h; Heating;
参考文献
Knuutinen, Juha S.; Kolehmainen, Erkki T.
Journal of Chemical & Engineering Data, 1983 , vol. 28, # 1 p. 139 - 141
反应条件
boron tribromide in dichloromethane T=0 - 20°C;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 10 p. 2553 - 2570
反应条件
1: 98 percent / TiCl4 / CH2Cl2 / 5 h / 20 °C 2: boron tribromide / CH2Cl2 / 0 - 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 10 p. 2553 - 2570
反应条件
pyridine in dichloromethane T=0 - 20°C;
参考文献
Yang, Cuijian; Edsall Jr., Richard; Harris, Heather A.; Zhang, Xiaochun; Manas, Eric S.; Mewshaw, Richard E.
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 10 p. 2553 - 2570
反应条件
hydrogenchloride; trifluoromethylsulfonic anhydride; trifluoromethanesulfonic acid anhydride in pyridine; (2S)-N-methyl-1-phenylpropan-2-amine hydrate; n-heptane
参考文献
Abbott Laboratories
Patent: US6878700 B1, 2005 ;
反应条件
potassium carbonate; dimethyl sulfate in N-methyl-acetamide; water
参考文献
Merck and Co., Inc.
Patent: US4356313 A1, 1982 ;
Title/Abstract Full Text Show Details
Merck and Co., Inc.
Patent: US4356314 A1, 1982 ;
