3-(2-噻吩)丙酸甲酯合成路线 （共 15 条）
反应条件
4-(N,N-dimethlyamino)pyridine; TEA in dichloromethane T=0°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 9 p. 2329 - 2332
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate P=2327.2 Torr; 11 h; Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 21 p. 3858 - 3872
反应条件
manganese(IV) oxide; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,4-dimethyl-1H-1,2,4-triazol-4-ium iodide in dichloromethane T=20°C; Inert atmosphere;
参考文献
Organic Letters, , vol. 10, # 19 p. 4331 - 4334
反应条件
10 Pd/C; hydrogen T=70°C; P=4500.45 Torr; 12 h;
参考文献
Chemical Papers, , vol. 67, # 1 p. 59 - 65,7
反应条件
1: 100 percent / H2 / Pd/C / methanol / 2585.74 Torr 2: 73 percent / TEA; DMAP / CH2Cl2 / 0 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 9 p. 2329 - 2332
反应条件
sulfuric acid 8 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 51, # 26 p. 5221 - 5226
反应条件
[Ir(dF(CF3)ppy)2(bpy)](PF6) in methanol; acetone T=20°C; Giese Free Radical Synthesis; 36 h; Inert atmosphereUV-irradiation;
参考文献
Advanced Synthesis and Catalysis, , vol. 354, # 18 p. 3414 - 3420
反应条件
1: thionyl chloride 2: 3 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 13 p. 3241 - 3246
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 13 p. 3241 - 3246
反应条件
1: With sodium hydroxide in tetrahydrofuran; water 3 h; Reflux; 2: With hydrogenchloride in tetrahydrofuran; water T=20°C;
参考文献
MacHara, Ales; Svoboda, Jiri
Chemical Papers, 2013 , vol. 67, # 1 p. 59 - 65,7
