1: 91 percent / trimethylsilyl azide, methyl triflate, molecular sieves / CH2Cl2 2: ethylenediamine View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: 90 percent / NaOMe / methanol / 4 h / 20 &deg;C / pH 8<br />2: 60 percent / tetrabutylammonium iodide; NaH / dimethylformamide / 0 - 20 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 70 percent / BF₃*Et₂O / CHCl₃ / 4 h / Heating<br />2: 90 percent / NaOMe / methanol / 4 h / 20 &deg;C / pH 8<br />3: 60 percent / tetrabutylammonium iodide; NaH / dimethylformamide / 0 - 20 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 4-DMAP, Ac₂O / CH₂Cl₂ <br />2: 72 percent / 4 Angstroem molecular sieves, TiCl₄ / CH₂Cl₂ / 1 h / Ambient temperature<br />3: 90 percent / CH₃ONa / methanol / 1.) r.t., 2 h, 2.) 3 deg C, overnight<br />4: 72 percent / NaH / dimethylformamide / Ambient temperature<br /> <br /> &nbsp;

<b>Multi-step reaction with 5 steps<br /> </b>1: 4-DMAP / CH₂Cl₂ / Ambient temperature<br />2: 4-DMAP, Ac₂O / CH₂Cl₂ <br />3: 72 percent / 4 Angstroem molecular sieves, TiCl₄ / CH₂Cl₂ / 1 h / Ambient temperature<br />4: 90 percent / CH₃ONa / methanol / 1.) r.t., 2 h, 2.) 3 deg C, overnight<br />5: 72 percent / NaH / dimethylformamide / Ambient temperature<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '8129999', constants.ctx, '0')">silver(l) oxide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '605365', constants.ctx, '0')">N,N-dimethyl-formamide</a> <br /> <br /> &nbsp;

<b>Multi-step reaction with 5 steps<br /> </b>1: 4-DMAP / CH₂Cl₂ / Ambient temperature<br />2: 4-DMAP, Ac₂O / CH₂Cl₂ <br />3: 72 percent / 4 Angstroem molecular sieves, TiCl₄ / CH₂Cl₂ / 1 h / Ambient temperature<br />4: 90 percent / CH₃ONa / methanol / 1.) r.t., 2 h, 2.) 3 deg C, overnight<br />5: 72 percent / NaH / dimethylformamide / Ambient temperature<br /> <br /> &nbsp;