2-氨基-3-羟基吡啶合成路线 （共 143 条）
参考文献
Prace Minist. Przem. chem.Chem.Abstr., <1952> Nr. 1, S. 1, 14
Prace Minist. Przem. chem.Chem.Abstr., <1954> 1337
反应条件
1: sulfuric acid; nitric acid / 20 - 30 °C 2: SnCl2; concentrated aqueous HCl View Scheme
参考文献
Pharmaceutical Bulletin, , vol. 5, p. 350,352
反应条件
1: concentrated sulfuric acid; fuming nitric acid / -15 °C / und folgenden 1-stdg.Erwaermen auf dem Wasserbad 2: tin (II)-chloride; concentrated hydrochloric acid 3: hydrogen bromide-glacial acetic acid / 130 °C View Scheme
参考文献
Chemische Berichte, , vol. 61, p. 1028
反应条件
1: tin (II)-chloride; concentrated hydrochloric acid 2: hydrogen bromide-glacial acetic acid / 130 °C View Scheme
参考文献
Chemische Berichte, , vol. 61, p. 1028
反应条件
toluene-4-sulfonic acid T=140 - 180°C;
参考文献
Doise; Blondeau; Sliwa
Synthetic Communications, 1992 , vol. 22, # 20 p. 2891 - 2901
反应条件
triethylamine in dichloromethane T=20°C;
参考文献
Henry; Guillaumet; Pujol
Tetrahedron Letters, 2004 , vol. 45, # 7 p. 1465 - 1468
反应条件
T=0°C; Beim kurzen Erhitzen des Reaktionsproduktes mit wss. NaOH;
参考文献
Fraser; Tittensor
Journal of the Chemical Society, <1957> 4625
反应条件
1: in (+)-Norephedrine T=185°C; 0.3 h; 2: With sodium hydrogencarbonate in (+)-Norephedrine; water
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2008/17688 A1, 2008 ;
Location in patent: Page/Page column 58 ;
反应条件
1: Py / 1 h / Ambient temperature 2: Cl2 / dimethylformamide / Ambient temperature 3: H2O 4: SOCl2 / CHCl3 5: methanol / 0.08 h / Heating View Scheme
参考文献
Ruefenacht,K. et al.
Helvetica Chimica Acta, 1976 , vol. 59, p. 1593 - 1612
反应条件
1: Py / 1 h / Ambient temperature 2: Cl2 / dimethylformamide / Ambient temperature View Scheme
参考文献
Ruefenacht,K. et al.
Helvetica Chimica Acta, 1976 , vol. 59, p. 1593 - 1612
