2-氨基-3-羟基吡啶合成路线 （共 143 条）
反应条件
2) 250 deg C; Multistep reaction;
参考文献
Doise; Dennin; Blondeau; Sliwa
Tetrahedron Letters, 1990 , vol. 31, # 8 p. 1155 - 1156
反应条件
1: 75 percent / 40percent aq. NaOH, Adogen 464 / CH2Cl2 / Ambient temperature 2: 70 percent / NaHCO3 / ethanol; H2O / 8 h / Heating View Scheme
参考文献
Rydzkowski, R.; Blondeau, D.; Sliwa, H.
Tetrahedron Letters, 1985 , vol. 26, # 21 p. 2571 - 2574
反应条件
in acetonitrile 12 h;
参考文献
Takeda, Kazuyoshi; Tsuboyama, Kanoko; Takayanagi, Hiroaki; Shirokami, Rie; Takeura, Masumi; Ogura, Haruo
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 9 p. 2334 - 2337
反应条件
in ethanol 20 h; Heating;
参考文献
Kaminski, James J.; Bristol, James A.; Puchalski, Chester; Lovey, Raymond G.; Elliott, Arthur J.; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 7 p. 876 - 892
反应条件
1: tetrabutylammomium bromide; sodium hydroxide / dichloromethane; water / 6 h / 20 °C 2: sulfuric acid; bromine; acetic acid / water / 0 - 20 °C View Scheme
参考文献
Chen, Dong; Liu, Yajing; Zhang, Shulan; Guo, Dexiang; Liu, Chunhong; Li, Sai; Gong, Ping
Archiv der Pharmazie, 2011 , vol. 344, # 3 p. 158 - 164
反应条件
1: 75 percent / 40percent aq. NaOH, Adogen 464 / CH2Cl2 / Ambient temperature 2: 70 percent / NaHCO3 / ethanol; H2O / 8 h / Heating 3: Pd(OH)2 / ethanol; cyclohexene / 12 h / Heating View Scheme
参考文献
Rydzkowski, R.; Blondeau, D.; Sliwa, H.
Tetrahedron Letters, 1985 , vol. 26, # 21 p. 2571 - 2574
反应条件
in ethanol 8 h; Heating;
参考文献
Rydzkowski, Richard; Blondeau, Dominique; Sliwa, H.; Caze, Claude
Journal of Chemical Research, Miniprint, 1986 , # 2 p. 670 - 688
反应条件
1: in glycerol T=142°C; 0.15 h; Microwave irradiation; 2: With acetic acid in ethanol; water; glycerol pH=3 - 4;
参考文献
Deligeorgiev, Todor G.; Kaloyanova, Stefka S.; Lesev, Nedyalko Y.; Vaquero, Juan J.
Monatshefte fur Chemie, 2011 , vol. 142, # 9 p. 895 - 899
反应条件
carbon disulfide; potassium hydroxide in methanol; water
参考文献
American Home Products Corporation
Patent: US4351832 A1, 1982 ;
反应条件
potassium hydroxide in ethanol Reflux;
参考文献
Shao, Ning; Aslanian, Robert; West Jr., Robert E.; Williams, Shirley M.; Wu, Ren-Long; Hwa, Joyce; Sondey, Christopher; Lachowicz, Jean; Palani, Anandan
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 5 p. 2075 - 2078
