2-甲氧基-5-氨基苯酚合成路线 （共 14 条）
反应条件
hydrogenchloride; tin
参考文献
Gazzetta Chimica Italiana, , vol. 37 II, p. 372
Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, , vol. <5> 21 II, p. 207
反应条件
hydrogenchloride; tin T=60°C; unter Lichtausschluss;
参考文献
Gazzetta Chimica Italiana, , vol. 41 I, p. 727
参考文献
Roy, Shyamali; Chatterjee, Smarajit K.; Chakraborty, D. P.; Roy, Shyamali
Journal of the Indian Chemical Society, 1985 , vol. 62, # 9 p. 673 - 675
反应条件
copper(I) bromide; sulfuric acid; hydrogen bromide; sodium nitrite 1.) MeOH, H2O, 0 deg C, 45 min, 2.) H2O, reflux, 1.5 h; Yield given. Multistep reaction;
参考文献
Meyers, A. I.; Snyder, Lawrence
Journal of Organic Chemistry, 1993 , vol. 58, # 1 p. 36 - 42
反应条件
formaldehyd; sodium cyanoborohydride in ethanol; hexane; ethyl acetate
参考文献
Biovitrum AB
Patent: US6465467 B1, 2002 ;
US 6465467 B1
反应条件
potassium iodide in 1,4-dioxane; water; ethyl acetate; N,N-dimethyl-formamide
参考文献
Rhone-Poulenc Rorer Limited
Patent: US5935978 A1, 1999 ;
US 5935978 A
Title/Abstract Full Text Show Details
Rhone-Poulenc Rorer Limited
Patent: US5679696 A1, 1997 ;
参考文献
Cross, R. Matthew; Namelikonda, Niranjan K.; Mutka, Tina S.; Luong, Lisa; Kyle, Dennis E.; Manetsch, Roman
Journal of Medicinal Chemistry, 2011 , vol. 54, # 24 p. 8321 - 8327
反应条件
in pyridine; DMF (N,N-dimethyl-formamide) T=20 - 60°C;
参考文献
METHYLGENE INC.
Patent: WO2005/92899 A1, 2005 ;
Location in patent: Page/Page column 140 ;
反应条件
1: 1.) H2SO4, NaNO2, 2.) Cu2Br2, HBr / 1.) MeOH, H2O, 0 deg C, 45 min, 2.) H2O, reflux, 1.5 h 2: 100 percent / K2CO3 / acetone / 24 h / Heating View Scheme
参考文献
Meyers, A. I.; Snyder, Lawrence
Journal of Organic Chemistry, 1993 , vol. 58, # 1 p. 36 - 42
