4-羟基-4-甲氧基联二苯合成路线 （共 41 条）
反应条件
potassium hydroxide in dimethyl sulfoxide T=20°C; 3 h;
参考文献
Orzeszko, Barbara; Melon-Ksyta, Dorota; Orzeszko, Andrzej
Synthetic Communications, 2002 , vol. 32, # 22 p. 3425 - 3429
反应条件
toluene-4-sulfonic acid in tetrahydrofuran Heating;
参考文献
DeSchepper, Richard E.; Swenton, John S.
Tetrahedron Letters, 1985 , vol. 26, # 40 p. 4831 - 4834
反应条件
bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide T=80°C; Stille cross-coupling reaction; 3 h;
参考文献
Journal of Organometallic Chemistry, , vol. 690, # 17 p. 3865 - 3877
反应条件
trifluorormethanesulfonic acid; trifluoroacetic acid T=0°C; 1 h;
参考文献
Journal of the American Chemical Society, , vol. 104, # 23 p. 6393 - 6397
反应条件
palladium diacetate; potassium carbonate; triphenylphosphine in water; isopropyl alcohol T=90°C; Suzuki coupling; 18 h; Inert atmosphere;
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 19 p. 6469 - 6481
反应条件
palladium 10 on activated carbon; tetra-n-butylammonium fluoride trihydrate T=150°C; Suzuki-Miyaura Coupling; 0.5 h; Microwave irradiationInert atmosphere;
参考文献
Schmidt, Bernd; Riemer, Martin
Journal of Organic Chemistry, 2014 , vol. 79, # 9 p. 4104 - 4118
反应条件
palladium 10 on activated carbon; potassium carbonate in water T=80°C; Suzuki-Miyaura Coupling; 2.5 h; Inert atmosphere;
参考文献
Schmidt, Bernd; Riemer, Martin
Journal of Organic Chemistry, 2014 , vol. 79, # 9 p. 4104 - 4118
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in ethylene glycol dimethyl ether T=80°C; 16 h; Further byproducts given;
参考文献
Tetrahedron Letters, , vol. 38, # 38 p. 6781 - 6784
反应条件
potassium hydroxide; water
参考文献
Journal of the American Chemical Society, , vol. 130, # 44 p. 14468 - 14470
反应条件
1: 4-MeOC6H4MgX, X = halide With zinc(II) chloride in tetrahydrofuran T=25°C; 0.25 h; Inert atmosphere; 2: 4-bromo-phenol With [(C10H13-1,3-(CH2P(Cy)2)2)Pd(Cl)] in tetrahydrofuran; 1,4-dioxane; 1-methyl-pyrrolidin-2-one T=100°C; Negishi cross-coupling reaction; Inert atmosphereResealed tube;
参考文献
Dalton Transactions, , vol. 40, # 35 p. 8996 - 9003
