1,4-二-(2-噻吩基)-1,3-丁二炔合成路线 （共 20 条）
反应条件
sodium sulfide in methanol Heating;
参考文献
Carpita, Adriano; Rossi, Renzo; Veracini, Carlo Alberto
Tetrahedron, 1985 , vol. 41, # 10 p. 1919 - 1930
反应条件
in N,N-dimethyl-formamide T=150°C; 1 h; Schlenk techniqueInert atmosphere;
参考文献
Synthesis (Germany), , vol. 45, # 12 art. no. SS-2013-H0207-OP, p. 1713 - 1718
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile
T=20°C; 2 h;
参考文献
Nasr-Esfahani, Mahboobeh; Mohammadpoor-Baltork, Iraj; Khosropour, Ahmad Reza; Moghadam, Majid; Mirkhani, Valiollah; Tangestaninejad, Shahram; Agabekov, Vladislav; Rudbari, Hadi Amiri
RSC Advances, 2014 , vol. 4, # 27 p. 14291 - 14296
反应条件
copper(l) iodide; iodine; potassium carbonate in dimethyl sulfoxide
T=50°C; 24 h; Inert atmosphere;
参考文献
Liu, De-Xian; Li, Fei-Long; Li, Hong-Xi; Gao, Jun; Lang, Jian-Ping
Tetrahedron, 2014 , vol. 70, # 14 p. 2416 - 2421
反应条件
copper(l) chloride in N,N-dimethyl-formamide
T=60°C; homo-coupling; 12 h;
参考文献
Nishihara, Yasushi; Ikegashira, Kazutaka; Hirabayashi, Kazunori; Ando, Jun-Ichi; Mori, Atsunori; Hiyama, Tamejiro
Journal of Organic Chemistry, 2000 , vol. 65, # 6 p. 1780 - 1787
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; 1,4-di(diphenylphosphino)-butane in dimethyl sulfoxide
T=30 - 80°C; 9 h; DarknessAerobic condition;
参考文献
Kim, Yong; Park, Ahbyeol; Park, Kyungho; Lee, Sunwoo
Tetrahedron Letters, 2011 , vol. 52, # 15 p. 1766 - 1769
反应条件
1: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine in tetrahydrofuran
T=20°C; Sonogashira coupling; 2 h;
2: With potassium fluoride; oxygen in tetrahydrofuran; methanol
T=50°C; Glaser coupling; 17 h;
参考文献
Merkul, Eugen; Urselmann, Dominik; Mueller, Thomas J. J.
European Journal of Organic Chemistry, 2011 , # 2 p. 238 - 242
反应条件
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); N-benzyl-N,N,N-triethylammonium chloride in sodium hydroxide; benzene
T=40°C; Addition; 48 h;
参考文献
Inoue, Shinobu; Jigami, Tetsuya; Nozoe, Hiroshi; Aso, Yoshio; Ogura, Fumio; Otsubo, Tetsuo
Heterocycles, 2000 , vol. 52, # 1 p. 159 - 170
反应条件
sodium hydroxide; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-benzyl-N,N,N-triethylammonium chloride in 1,4-dioxane; water
1.5 h; Heating;
参考文献
Sarkar, Abhijit; Okada, Shuji; Nakanishi, Hachiro; Matsuda, Hiro
Helvetica Chimica Acta, 1999 , vol. 82, # 1 p. 138 - 141
反应条件
N,N,N',N,-tetramethylethylenediamine; oxygen; copper(l) chloride in acetone
4 h;
参考文献
Neenan, Thomas X.; Whitesides, George M.
Journal of Organic Chemistry, 1988 , vol. 53, # 11 p. 2489 - 2496
