hydrogenchloride in methanol T=25°C; 48 h;

potassium carbonate; sodium iodide in acetone 48 h; Heating;

potassium hydroxide 3 h; Heating;

potassium hydroxide und Erwaermen des Reaktionsprodukts mit 2-Chlor-aethanol;

1.1: triethylamine / diethyl ether / 17 h / 0 - 20 °C 1.2: 56 percent / aq. NaHCO3 / diethyl ether / 3 h / Heating 2.1: 92 percent / potassium carbonate; NaI / acetone / 36 h / Heating 3.1: 93 percent / aq. potassium hydroxide / 3 h / Heating View Scheme

pyridine T=176°C;