oxygen; palladium diacetate in N,N-dimethyl acetamide T=120°C; Reagent/catalystSolvent;

1: With zinc in tetrahydrofuran Blaise reaction; 2.5 h; RefluxInert atmosphere; 2: With tetrakis(triphenylphosphine) palladium(0); potassium tert-butylate in tetrahydrofuran; N,N-dimethyl-formamide T=120°C; 15 h; Inert atmosphere;

1: 41 percent / MgSO4, Na2HPO4 / I2 2: 100 percent / Pd(OAc)2, PPh3, NEt3 / acetonitrile / 25.5 h / further phenyl-substituted starting materials; different quantity of Pd(OAc)2, further triarylphosphines View Scheme

1: 41 percent / MgSO4, Na2HPO4 / I2 2: 100 percent / Pd(OAc)2, PPh3, NEt3 / acetonitrile / 25.5 h / further phenyl-substituted starting materials; different quantity of Pd(OAc)2, further triarylphosphines View Scheme

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / |Inert atmosphere 1.2: 1 h / -78 - 20 °C / |Inert atmosphere 2.1: trifluoroacetic acid / dichloromethane / 1 h / 0 - 20 °C / |Inert atmosphere 3.1: palladium diacetate; oxygen / N,N-dimethyl acetamide / 120 °C View Scheme

1: trifluoroacetic acid / dichloromethane / 1 h / 0 - 20 °C / |Inert atmosphere 2: palladium diacetate; oxygen / N,N-dimethyl acetamide / 120 °C View Scheme