N-(3-羟吡啶-4-基)棕榈酰胺合成路线 （共 6 条）
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=-78 - 0°C; Inert atmosphere; 2: With trimethyl borane in tetrahydrofuran; hexane T=-78 - 0°C; 3: With dihydrogen peroxide; acetic acid in tetrahydrofuran; hexane; water T=0 - 20°C; 18.5 h;
参考文献
Ahn, Sung Oh; Park, Chan Hee; Im, Jun Hwan; Lee, Soon Ok; Lee, Kyoung June; Cho, Seong Wook; Ko, Kwang Seok; Han, Sun Young; Lee, Won Il
Patent: US2011/28467 A1, 2011 ;
Location in patent: Page/Page column 16 ;
US 20110028467 A1
反应条件
1: 85 percent / triethylamine / CH2Cl2 2: n-BuLi; trimethylborate; H2O2 View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 40, # 1 p. 15 - 23
反应条件
1: 85 percent / triethylamine / CH2Cl2 2: n-BuLi; trimethylborate; H2O2 View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 40, # 1 p. 15 - 23
反应条件
1: With hydrogenchloride in water T=20 - 90°C; 2: With sodium hydroxide in water T=0°C;
参考文献
Ahn, Sung Oh; Park, Chan Hee; Im, Jun Hwan; Lee, Soon Ok; Lee, Kyoung June; Cho, Seong Wook; Ko, Kwang Seok; Han, Sun Young; Lee, Won Il
Patent: US2011/28467 A1, 2011 ;
Location in patent: Page/Page column 16 ;
US 20110028467 A1
反应条件
1: HCl; NaOH / H2O 2: 79 percent / ethanol / 18 h / Heating 3: 73 percent / potassium carbonate / dimethylformamide / 1 h View Scheme
参考文献
Chu-Moyer; Berger
Journal of Organic Chemistry, 1995 , vol. 60, # 17 p. 5721 - 5725
反应条件
1: HCl; NaOH / H2O 2: 79 percent / ethanol / 18 h / Heating View Scheme
参考文献
Chu-Moyer; Berger
Journal of Organic Chemistry, 1995 , vol. 60, # 17 p. 5721 - 5725
