2-甲基硫基 [ 1,3 ] 恶唑酮[5,4-C]吡啶合成路线 （共 5 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide 1 h;
参考文献
Chu-Moyer; Berger
Journal of Organic Chemistry, 1995 , vol. 60, # 17 p. 5721 - 5725
反应条件
1: 79 percent / ethanol / 18 h / Heating 2: 73 percent / potassium carbonate / dimethylformamide / 1 h View Scheme
参考文献
Chu-Moyer; Berger
Journal of Organic Chemistry, 1995 , vol. 60, # 17 p. 5721 - 5725
反应条件
1: n-BuLi; trimethylborate; H2O2 2: HCl; NaOH / H2O 3: 79 percent / ethanol / 18 h / Heating 4: 73 percent / potassium carbonate / dimethylformamide / 1 h View Scheme
参考文献
Chu-Moyer; Berger
Journal of Organic Chemistry, 1995 , vol. 60, # 17 p. 5721 - 5725
反应条件
1: HCl; NaOH / H2O 2: 79 percent / ethanol / 18 h / Heating 3: 73 percent / potassium carbonate / dimethylformamide / 1 h View Scheme
参考文献
Chu-Moyer; Berger
Journal of Organic Chemistry, 1995 , vol. 60, # 17 p. 5721 - 5725
反应条件
1: 85 percent / triethylamine / CH2Cl2 2: n-BuLi; trimethylborate; H2O2 3: HCl; NaOH / H2O 4: 79 percent / ethanol / 18 h / Heating 5: 73 percent / potassium carbonate / dimethylformamide / 1 h View Scheme
参考文献
Walczyski, Krzysztof; Zuiderveld, Obbe P.; Timmerman, Henk
European Journal of Medicinal Chemistry, 2005 , vol. 40, # 1 p. 15 - 23
