2-[4-(4-氯-丁基)-苯基]-2-甲基-丙酸合成路线 （共 17 条）
反应条件
hydrogenchloride; tetrabutylammomium bromide in acetonitrile T=-10°C; 6 h; Electrolysis;
参考文献
Merrell Pharmaceuticals Inc.
Patent: US6340761 B1, 2002 ;
Location in patent: Page column 79-80 ;
反应条件
hydrogenchloride in ethanol 2.5 h; Heating / reflux;
参考文献
Merrell Pharmaceuticals, Inc.
Patent: US6348597 B2, 2002 ;
Location in patent: Page column 79 ;
反应条件
hydrogenchloride in dichloromethane
参考文献
Merrell Pharmaceuticals Inc.
Patent: US6242606 B1, 2001 ;
反应条件
hydrogenchloride T=60°C; 2.5 h; Heating / reflux;
参考文献
Merrell Pharmaceuticals Inc.
Patent: US6340761 B1, 2002 ;
Location in patent: Example 27 ;
反应条件
hydrogenchloride in dichloromethane
参考文献
Merrell Pharmaceuticals Inc.
Patent: US6242606 B1, 2001 ;
反应条件
potassium carbonate in acetonitrile T=40°C; 0.75 h; Heating / reflux;
参考文献
Merrell Pharmaceuticals, Inc.
Patent: US6348597 B2, 2002 ;
Location in patent: Page column 79 ;
反应条件
hydrogenchloride 0.7 h; Heating / reflux;
参考文献
Merrell Pharmaceuticals, Inc.
Patent: US6348597 B2, 2002 ;
Location in patent: Page column 79 ;
