1: water; acetic acid; potassium permanganate / acetone / 7 h / 25 - 45 °C 2: hydrogenchloride / 7 h / 40 - 45 °C 3: sodium tetrahydroborate / ethanol / 7 h / 25 - 30 °C 4: potassium hydrogencarbonate; potassium iodide / N,N-dimethyl-formamide / 16 h / |Reflux 5: methanol; sodium hydroxide / 6 h / |Reflux View Scheme

1: water; acetic acid; potassium permanganate / acetone / 7 h / 25 - 45 °C 2: hydrogenchloride / 7 h / 40 - 45 °C View Scheme

1: potassium permanganate; acetic acid / water; acetone / 0 - 20 °C 2: hydrogenchloride; methanol / 7 h / 40 - 45 °C View Scheme

ruthenium trichloride; sodium periodate in tetrachloromethane; water; acetonitrile T=20°C; 1 h;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11342940', constants.ctx, '0')">sodium hydroxide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1718733', constants.ctx, '0')">ethanol</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a> <br />0.5&nbsp;h;&nbsp;&nbsp;Heating / reflux;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1.1: AlCl₃, aluminium chloride; Propylene glycol / methyl acetate / 0 - 5 &deg;C<br />2.1: AlCl₃, aluminium chloride / dichloromethane / 2.33 h / -5 - 0 &deg;C<br />2.2: 5 h / 0 &deg;C<br />3.1: methanol; sodium hydroxide / 4 h / 25 - 30 &deg;C<br /> <br /> &nbsp;