(2-二苯甲基氧基羰基氨基-6-氧代-1,6-二氢嘌呤-9-基)-乙酸合成路线 （共 4 条）
反应条件
sodium hydride; 3-hydroxy-propionitrile in tetrahydrofuran T=-78 - 20°C;
参考文献
Debaene, Francois; Winssinger, Nicolas
Organic Letters, 2003 , vol. 5, # 23 p. 4445 - 4447
反应条件
1.1: diisopropylethylamine / tetrahydrofuran / 0.5 h / 0 °C 1.2: 63.8 percent / tetrahydrofuran / 12 h / 0 - 20 °C 2.1: 86.5 percent / sodium hydride; 3-hydroxypropionitrile / tetrahydrofuran / -78 - 20 °C View Scheme
参考文献
Debaene, Francois; Winssinger, Nicolas
Organic Letters, 2003 , vol. 5, # 23 p. 4445 - 4447
反应条件
1.1: 67.7 percent / potassium carbonate / dimethylformamide / 0 - 20 °C 2.1: diisopropylethylamine / tetrahydrofuran / 0.5 h / 0 °C 2.2: 63.8 percent / tetrahydrofuran / 12 h / 0 - 20 °C 3.1: 86.5 percent / sodium hydride; 3-hydroxypropionitrile / tetrahydrofuran / -78 - 20 °C View Scheme
参考文献
Debaene, Francois; Winssinger, Nicolas
Organic Letters, 2003 , vol. 5, # 23 p. 4445 - 4447
反应条件
1.1: diisopropylethylamine / tetrahydrofuran / 0.5 h / 0 °C 1.2: 63.8 percent / tetrahydrofuran / 12 h / 0 - 20 °C 2.1: 86.5 percent / sodium hydride; 3-hydroxypropionitrile / tetrahydrofuran / -78 - 20 °C View Scheme
参考文献
Debaene, Francois; Winssinger, Nicolas
Organic Letters, 2003 , vol. 5, # 23 p. 4445 - 4447
