(4-噻吩-2-苯基)甲醇合成路线 （共 55 条）
反应条件
C40H36N2O2Pd(2+)*2C2H4O2; potassium carbonate; 2,2,2-trimethylacetic acid in N,N-dimethyl acetamide
T=100°C; 24 h; Inert atmosphereSchlenk technique; regioselective reaction;
参考文献
Li, Yabo; Wang, Jingran; Huang, Mengmeng; Wang, Zhiwei; Wu, Yusheng; Wu, Yangjie
Journal of Organic Chemistry, 2014 , vol. 79, # 7 p. 2890 - 2897
反应条件
1: POCl3 / 1,2-dichloro-ethane / 17 h / Heating
2: 76 percent / NaOH; Ag2O / H2O / 20 - 50 °C
3: 95 percent / H2SO4 / toluene / 7 h / Heating
View Scheme
参考文献
Noguchi, Toshiya; Hasegawa, Masahiro; Tomisawa, Kazuyuki; Mitsukuchi, Morihiro
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 22 p. 4729 - 4742
反应条件
carbon disulfide; tin(IV) chloride
参考文献
Buu-Hoi; Hoan
Recueil des Travaux Chimiques des Pays-Bas, 1950 , vol. 69, p. 1455,1466
反应条件
trichlorophosphate in 1,2-dichloro-ethane
Vilsmeier reaction; 17 h; Heating;
参考文献
Noguchi, Toshiya; Hasegawa, Masahiro; Tomisawa, Kazuyuki; Mitsukuchi, Morihiro
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 22 p. 4729 - 4742
反应条件
1: POCl3 / 1,2-dichloro-ethane / 17 h / Heating
2: 76 percent / NaOH; Ag2O / H2O / 20 - 50 °C
View Scheme
参考文献
Buu-Hoi; Hoan
Recueil des Travaux Chimiques des Pays-Bas, 1950 , vol. 69, p. 1455,1466
