5-氰基-1H-吲哚-2-羧酸合成路线 （共 7 条）
反应条件
1,4-diaza-bicyclo[2.2.2]octane; palladium diacetate in N,N-dimethyl-formamide T=105°C; 4 h; Inert atmosphere;
参考文献
Robertson, William M.; Kastrinsky, David B.; Hwang, Inkyu; Boger, Dale L.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 9 p. 2722 - 2725
参考文献
Pfizer, Inc.
Patent: US6107329 A1, 2000 ;
反应条件
1: I2; Ag2SO4 / ethanol / 16 h / 20 °C 2: DABCO; Pd(OAc)2 / dimethylformamide / 4 h / 105 °C View Scheme
参考文献
Robertson, William M.; Kastrinsky, David B.; Hwang, Inkyu; Boger, Dale L.
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 9 p. 2722 - 2725
反应条件
1: ethanolic sodium ethylate 2: zinc-powder; aqueous acetic acid View Scheme
参考文献
Lindwall; Mantell
Journal of Organic Chemistry, 1953 , vol. 18, p. 345,356
反应条件
1: zinc-powder; aqueous acetic acid View Scheme
参考文献
Lindwall; Mantell
Journal of Organic Chemistry, 1953 , vol. 18, p. 345,356
反应条件
thionyl chloride T=20°C; Reflux;
参考文献
Castro Pineiro, Jose Luis; Lin, Xichen; Liu, Qian; Meng, Kevin; Ren, Feng; Vesey, David R.; Zhao, Baowei
Patent: US2010/29729 A1, 2010 ;
Location in patent: Page/Page column 20 ;
参考文献
Journal of Organic Chemistry, , vol. 18, p. 345,356
