2,4,5-三氯苯基氯甲酸酯合成路线 （共 10 条）
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane 1.) 0 deg C, 3 h, 2.) 0-20 deg C, 6 h, 3.) reflux, 2 h;
参考文献
Konakahara; Ozaki; Sato; Gold
Synthesis, 1993 , # 1 p. 103 - 106
反应条件
N,N-dimethyl-aniline in toluene T=80°C; 3 h;
参考文献
McCormick, Joan E.; McElhinney, R. Stanley; McMurry, T. Brian H.
Journal of Chemical Research, Miniprint, 1991 , p. 1216 - 1239
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane bis(trichloromethyl) carbonate as phosgene source; other substrates;
参考文献
Konakahara; Ozaki; Sato; Gold
Synthesis, 1993 , # 1 p. 103 - 106
反应条件
potassium hydroxide in diethyl ether 0.75 h;
参考文献
Johnston, Thomas P.; Kussner, Conrad L.; Carter, Ronald L.; Frye, Jerry L.; Lomax, Nancita R.; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1422 - 1426
反应条件
(i) DMF, (ii) /BRN= 2222826/, Et3N; Multistep reaction;
参考文献
Itoh,M.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, # 4 p. 784 - 788
反应条件
quinoline in dichloromethane
参考文献
Broadbent,W. et al.
Journal of the Chemical Society [Section] C: Organic, 1967 , p. 2632 - 2636
反应条件
triethylamine in dichloromethane
参考文献
Sanofi
Patent: US4883903 A1, 1989 ;
反应条件
potassium hydroxide in diethyl ether
0.75 h;
参考文献
Johnston, Thomas P.; Kussner, Conrad L.; Carter, Ronald L.; Frye, Jerry L.; Lomax, Nancita R.; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1422 - 1426
反应条件
potassium hydroxide in diethyl ether
0.75 h;
参考文献
Johnston, Thomas P.; Kussner, Conrad L.; Carter, Ronald L.; Frye, Jerry L.; Lomax, Nancita R.; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 11 p. 1422 - 1426
反应条件
N-ethyl-N,N-diisopropylamine in dichloromethane
T=0 - 3°C; 48 h;
参考文献
Konakahara; Ozaki; Sato; Gold
Synthesis, 1993 , # 1 p. 103 - 106
