BOC-N-甲基-L-丙氨酸合成路线 （共 11 条）
反应条件
sodium hydride in tetrahydrofuran T=0 - 20°C;
参考文献
Loscher, Sebastian; Schobert, Rainer
Chemistry - A European Journal, 2013 , vol. 19, # 32 p. 10619 - 10624
反应条件
1: With sodium hydroxide in methanol; water T=20°C; 4 h; 2: With citric acid in water pH=3;
参考文献
Tetrahedron, , vol. 68, # 35 p. 7070 - 7076
反应条件
sodium hydroxide in 1,4-dioxane; water 5 h; Ambient temperature;
参考文献
Cheung, Kam Sing; Boisvert, William; Lerner, Stephen A.; Johnston, Michael
Journal of Medicinal Chemistry, 1986 , vol. 29, # 10 p. 2060 - 2068
反应条件
hydrogen; palladium on activated charcoal in methanol Yield given;
参考文献
Tetrahedron Letters, , vol. 39, # 14 p. 1985 - 1986
反应条件
potassium hydroxide; tetra(n-butyl)ammonium hydrogensulfate in tetrahydrofuran 0.5 h; Ambient temperature;
参考文献
Belagali, Shiddappa L.; Mathew, Thankamma; Himaja, M.; Kocienski, Philip
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995 , vol. 34, # 1 p. 45 - 47
参考文献
Journal of Physical Organic Chemistry, , vol. 17, # 5 p. 448 - 457
反应条件
1: triethylamine / dioxane; H2O / 4 h / Ambient temperature 2: NaH / tetrahydrofuran / 24 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 47, # 29 p. 5453 - 5462
反应条件
1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.17 h / 20 °C 1.2: 10 h / 60 °C 2.1: sodium hydroxide / methanol; water / 4 h / 20 °C 2.2: pH 3 View Scheme
参考文献
Tetrahedron, , vol. 68, # 35 p. 7070 - 7076
反应条件
trifluoroacetic acid
参考文献
Olsen
The Journal of organic chemistry, 1970 , vol. 35, # 6 p. 1912 - 1915
参考文献
Loscher, Sebastian; Schobert, Rainer
Chemistry - A European Journal, 2013 , vol. 19, # 32 p. 10619 - 10624
