2,4,5-三氟-3-乙氧基苯甲酸合成路线 (共 2 条)
反应条件
sodium hydroxide in methanol 3 h; Ambient temperature;
参考文献
Sanchez, Joseph P.; Gogliotti, Rocco D.; Domagala, John M.; Gracheck, Stephen J.; Huband, Michael D.; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 22 p. 4478 - 4487
反应条件
1: 92 percent / NaH / dimethylformamide / 18 h 2: 79 percent / 1.0 N aq. NaOH / methanol / 3 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 22 p. 4478 - 4487