4,5-二溴-1,2-二甲基-1H-咪唑合成路线 (共 3 条)
反应条件
sodium hydroxide in water T=40°C;
参考文献
Bahnous, Mebarek; Bouraiou, Abdelmalek; Chelghoum, Meryem; Bouacida, Sofiane; Roisnel, Thierry; Smati, Farida; Bentchouala, Chafia; Gros, Philippe C.; Belfaitah, Ali
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 5 p. 1274 - 1278
反应条件
bromine; potassium hydrogencarbonate; N,N-dimethyl-formamide in N,N-dimethyl-formamide T=0 - 100°C; 3 h;
参考文献
Bahnous, Mebarek; Mouats, Chabane; Fort, Yves; Gros, Philippe C.
Tetrahedron Letters, 2006 , vol. 47, # 12 p. 1949 - 1951
反应条件
2,2,6,6-tetramethyl-piperidine-N-oxyl; sodium hypochlorite; sodium hydrogencarbonate; potassium bromide in dichloromethane T=0°C; 6 h;
参考文献
Webel, Matthias; Palmer, Andreas Marc; Scheufler, Christian; Haag, Dieter; Mueller, Bernd
Organic Process Research and Development, 2010 , vol. 14, # 1 p. 142 - 151