N,N-二乙基苯甲酰胺合成路线 （共 244 条）
反应条件
lithium in tetrahydrofuran
5 h; Ambient temperatureultrasonic bath;
参考文献
Karaman, Rafik; Fry, James L.
Tetrahedron Letters, 1990 , vol. 31, # 7 p. 941 - 944
反应条件
N,N,N',N,-tetramethylethylenediamine; sec.-butyllithium; magnesium bromide in tetrahydrofuran
other benzamides, other aldehydes;
参考文献
Sibi; Miah; Snieckus
Journal of Organic Chemistry, 1984 , vol. 49, # 5 p. 737 - 742
反应条件
Yield given. Multistep reaction;
参考文献
Reed, J. N.; Snieckus, V.
Tetrahedron Letters, 1983 , vol. 24, # 36 p. 3795 - 3798
反应条件
sodium in tetrahydrofuran
5 h; Ambient temperatureultrasonic bath;
参考文献
Karaman, Rafik; Fry, James L.
Tetrahedron Letters, 1990 , vol. 31, # 7 p. 941 - 944
反应条件
lithium in tetrahydrofuran
5 h; Ambient temperatureultrasonic bath;
参考文献
Karaman, Rafik; Fry, James L.
Tetrahedron Letters, 1990 , vol. 31, # 7 p. 941 - 944
反应条件
N,N,N',N,-tetramethylethylenediamine; sec.-butyllithium in diethyl ether
1.) -78 deg C, 1 h, 2.) -78 deg C -> RT, 12 h;
参考文献
Watanabe; Snieckus
Journal of the American Chemical Society, 1980 , vol. 102, # 4 p. 1457 - 1460
反应条件
Yield given. Multistep reaction;
参考文献
Ray, Jayanta K.; Harvey, Ronald G.
Journal of Organic Chemistry, 1982 , vol. 47, # 17 p. 3335 - 3336
反应条件
water in hexane
stirring (-20°C, 1.5 h), heating to 20°C, decompn. with water; extn. of org. layer (ether), drying of extract (over MgSO4), fractionaldistn.; elem. anal.;
参考文献
Bravo-Zhivotovskii, D. A.; Pigarev, S. D.; Vyazankina, O. A.; Kalikhman, I. D.; Vyazankin, N. S.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1982 , vol. 31, # 4 p. 841 - 843
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1982 , # 4 p. 949 - 951
反应条件
N,N,N',N,-tetramethylethylenediamine; sec.-butyllithium
1) THF, cyclohexane, -78 deg C, 1 h, 2) to room temperature, 12 h; Yield given. Multistep reaction;
参考文献
De Silva; Reed; Billedeau; Wang; Norris; Snieckus
Tetrahedron, 1992 , vol. 48, # 23 p. 4863 - 4878
反应条件
1: 1.) s-BuLi, TMEDA / 1.) cyclohexane, THF, -78 deg C, 1 h, 2.) THF, cyclohexane, from -78 deg C to RT, 8 h
2: 1.) s-BuLi, TMEDA / 1.) cyclohexane, THF, -78 deg C, 1 h, 2.) THF, cyclohexane, from -78 deg C to RT, 8 h
View Scheme
参考文献
Mills, Robert J.; Taylor, Nicholas J.; Snieckus, Victor
Journal of Organic Chemistry, 1989 , vol. 54, # 18 p. 4372 - 4385
