4-乙酰氨基丙正离子基酰苯合成路线 （共 12 条）
反应条件
1: nitric acid; sulfuric acid / 0.67 h / -10 °C
2: hydrogenchloride; water / 1 h / |Reflux
3: hydrogen; palladium 10 on activated carbon / methanol / 1 h / 20 °C / 760.05 Torr
View Scheme
参考文献
CENTAURUS BIOPHARMA CO., LTD.; XIAO, Dengming; ZHU, Li; HU, Yuandong; YU, Rong; HU, Wei; ZHAO, Na; PENG, Yong; LUO, Hong; HAN, Yongxin
Patent: WO2013/97773 A1, 2013 ;
反应条件
1: With bromine in chloroform
2: With sodium carbonate in water
T=20°C; pH=8; 24 h;
参考文献
Wang, Lisheng; Zhou, Hongxiang; Yang, Bin; Chen, Zhigang; Yang, Hua
Medicinal Chemistry Research, 2011 , vol. 20, # 3 p. 287 - 292
