3-[(1S,2S,5R)-7-氧代-3-硫杂-6,8-二氮杂双环[3.3.0]辛-2-基]丙酸合成路线 （共 3 条）
反应条件
potassium phosphate buffer T=30°C; 5 h; bacterial degradation by Mycoplana sp. No. 166; Product distribution;
参考文献
Osakai, Miyako; Izumi, Yoshikazu; Nakamura, Kaoru; Yamada, Hideaki
Agricultural and Biological Chemistry, 1986 , vol. 50, # 2 p. 311 - 316
反应条件
1: H2SO4 / 1 h / Heating 2: LiBH4 / tetrahydrofuran / 3.5 h / Heating 3: HBr / acetic acid / 0.5 h / 100 °C 4: (i) Na, (ii) /BRN= 4047078/, (iii) aq. Ba(OH)2, MeOH View Scheme
参考文献
Confalone,P.N. et al.
Journal of the American Chemical Society, 1977 , vol. 99, p. 7020 - 7026
反应条件
1: H2SO4 / 1 h / Heating 2: LiBH4 / tetrahydrofuran / 3.5 h / Heating 3: HBr / acetic acid / 0.5 h / 100 °C 4: (i) Na, (ii) /BRN= 4047078/, (iii) aq. Ba(OH)2, MeOH 5: aq. NaOH / 0.5 h / 180 °C View Scheme
参考文献
Confalone,P.N. et al.
Journal of the American Chemical Society, 1977 , vol. 99, p. 7020 - 7026
