1-苯基-4,5-二氯-6-哒酮合成路线 (共 35 条)
反应条件
hydrogenchloride; water 3 h; Reflux;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 17, # 20 p. 7174 - 7185
反应条件
1: aniline With hydrogenchloride; sodium nitrite in water T=-5 - 0°C; 0.5 h; 2: With hydrogenchloride; tin(ll) chloride in water T=0°C; 2 h; 3: 3,4-dichloro-5-hydroxyfuran-2(5H)-one in water T=80 - 90°C;
参考文献
Tetrahedron Letters, , vol. 47, # 49 p. 8733 - 8735
参考文献
Journal of the American Chemical Society, , vol. 75, p. 1909,76 <1954> 6417
反应条件
2: acetic acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 75, p. 1909,76 <1954> 6417
反应条件
sodium hydroxide T=100°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 6 p. 1819 - 1822
反应条件
zinc(II) chloride; lead(IV) acetate 20 h; Heating; Product distribution; Further Variations:Reagents;
参考文献
Tetrahedron Letters, , vol. 45, # 48 p. 8781 - 8784
参考文献
Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 186, # 1 p. 81 - 87
反应条件
potassium hydroxide in 1,4-dioxane; water T=25°C; 0.25 h;
参考文献
Lyga, John W.
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 1757 - 1760
反应条件
potassium carbonate in methanol
参考文献
Abbott Laboratories
Patent: US6307047 B1, 2001 ;
反应条件
sodium hydride 1 h; Ambient temperature;
参考文献
Lyga, John W.
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 1757 - 1760