10H-吩噻嗪-10-丙腈合成路线 （共 11 条）
反应条件
tetra(n-butyl)ammonium hydroxide in 1,4-dioxane; water Michael addition; 1 h; Heating;
参考文献
Organic letters, , vol. 2, # 22 p. 3413 - 3416
反应条件
potassium hydroxide in methanol; ethanol T=60°C; 0.5 h;
参考文献
Zhang, Yanling; Eric Ballard; Zheng, Shi-Long; Gao, Xingming; Ko, Ko-Chun; Yang, Hsiuchin; Brandt, Gary; Lou, Xinhui; Tai, Phang C.; Lu, Chung-Dar; Wang, Binghe
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 3 p. 707 - 711
反应条件
1: NaOH / Heating 2: H+ / Heating 3: N2H4 / ethanol / Heating View Scheme
参考文献
Sawizkaja et al.
Zhurnal Obshchei Khimii, 1956 , vol. 26, p. 2900,2903; engl. Ausg. S. 3227, 3229
反应条件
1: water; sodium hydroxide / methanol / 15 h / Reflux 2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 24 h / 20 °C View Scheme
参考文献
Dumitriu, Gina-Mirabela; Ghinet, Alina; Bicu, Elena; Rigo, Benoit; Dubois, Joelle; Farce, Amaury; Belei, Dalila
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 14 p. 3180 - 3185
反应条件
1: 3.7 g / 30percent H2O2 / acetic acid / 15 h / Heating
2: aqueous NaOH
View Scheme
参考文献
Catsoulacos, P.; Pelecanou, M.; Camoutsis, Ch.
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 5 p. 1437 - 1440
反应条件
1: phosphorus pentachloride / benzene / 1 h / 5 - 20 °C
2: 89 percent / benzene / 0.5 h
3: 65 percent / diborane / tetrahydrofuran
View Scheme
参考文献
Owen, Terence C.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 265 - 266
反应条件
1: phosphorus pentachloride / benzene / 1 h / 5 - 20 °C
2: 89 percent / benzene / 0.5 h
View Scheme
参考文献
Owen, Terence C.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 265 - 266
反应条件
cobalt; N,N-dimethyl-formamide; silver carbonate
Hydrogenation.Reagens 4: CuCl; Reagens 5: Kupfer-Pulver;
参考文献
Chem. Fabr. Promonta
Patent: GB901187 , 1958 ;
反应条件
1: phosphorus pentachloride / benzene / 1 h / 5 - 20 °C
2: 93 percent / benzene / 0.5 h
3: 78 percent / diborane / tetrahydrofuran
View Scheme
参考文献
Brufani; Cesta; Filocamo; Lappa; Marta; Pomponi; Meroni; Pagella
Farmaco, 1992 , vol. 47, # 5 p. 585 - 597
反应条件
cobalt; N,N-dimethyl-formamide; silver carbonate
Hydrogenation.Reagens 4:CuCl; Reagens 5: Kupfer-Pulver;
参考文献
Chem. Fabr. Promonta
Patent: GB901187 , 1958 ;
