反应条件
1: PBr3 / diethyl ether / 3 h / Ambient temperature 2: 1.) n-BuLi, 2.) TMEDA / 1.) THF, hexane, -20 deg C, 90 min; -80 deg C, 2 h, 2.) -20 deg C, 16 h 3: 62 percent / NiCl2*6H2O, NaBH4, 2 N aq. KOH / tetrahydrofuran; methanol 4: 82 percent / H2 / 5percent Pd/C / ethyl acetate / 16 h / Ambient temperature View Scheme
参考文献
Van Oeveren; Jansen; Feringa
Journal of Organic Chemistry, 1994 , vol. 59, # 20 p. 5999 - 6007
