1-溴-4-氟-2-甲基-5-硝基苯合成路线 （共 3 条）
反应条件
sulfuric acid; potassium nitrate T=0 - 20°C; 2 h;
参考文献
GLAXO GROUP LIMITED
Patent: WO2007/36718 A2, 2007 ;
Location in patent: Page/Page column 57-58 ;
WO 2007/036718 A2
反应条件
hydrogen in ethanol P=2062.71 Torr;
参考文献
DECIPHERA PHARMACEUTICALS, LLC; ELI LILLY AND COMPANY; FLYNN, Daniel L.; KAUFMAN, Michael D.; VOGETI, Lakshminarayana; WISE, Scott C.; LU, Wei-Ping; SMITH, Bryan D.; CALDWELL, Timothy M.; PATT, William C.; HENRY, James Robert; HIPSKIND, Philip Arthur; PENG, Sheng-Bin
Patent: WO2013/134298 A1, 2013 ;
Location in patent: Page/Page column 42 ;
参考文献
Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;
