n-boc-3-氧代吡咯烷-2-羧酸乙酯合成路线 （共 7 条）
反应条件
potassium tert-butylate in toluene T=0°C; 0.5 h;
参考文献
Knight, David W.; Sibley, A. William
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 15 p. 2179 - 2187
反应条件
dirhodium tetraacetate in toluene T=110°C; Inert atmosphere;
参考文献
Hovey, M. Todd; Eklund, Emily J.; Pike, Robert D.; Mainkar, Anshul A.; Scheerer, Jonathan R.
Organic Letters, 2011 , vol. 13, # 5 p. 1246 - 1249
反应条件
lithium hexamethyldisilazane in tetrahydrofuran T=-78°C; 2 h;
参考文献
Pellegrini, Nadia; Schmitt, Martine; Guery, Sebastien; Bourguignon, Jean-Jacques
Tetrahedron Letters, 2002 , vol. 43, # 17 p. 3243 - 3246
反应条件
1: 90 percent / aq. NaOH / CHCl3 / 11 h / 0 - 20 °C 2: 37 percent / t-BuOK / toluene / 1.42 h / 0 °C View Scheme
参考文献
Calugi, Chiara; Trabocchi, Andrea; Lalli, Claudia; Guarna, Antonio
European Journal of Medicinal Chemistry, 2012 , vol. 56, p. 96 - 107
反应条件
1: 90 percent / aq. NaOH / CHCl3 / 11 h / 0 - 20 °C 2: 37 percent / t-BuOK / toluene / 1.42 h / 0 °C View Scheme
参考文献
Cooper, Jeremy; Gallagher, Peter T.; Knight, David W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 12 p. 1313 - 1318
反应条件
potassium tert-butylate in toluene T=0°C; 0.5 h;
参考文献
Cooper, Jeremy; Gallagher, Peter T.; Knight, David W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 12 p. 1313 - 1318
反应条件
1: lithium hexamethyldisilazane / tetrahydrofuran / 3 h / -78 °C / Inert atmosphere 2: dirhodium tetraacetate / toluene / 110 °C / Inert atmosphere View Scheme
参考文献
Hovey, M. Todd; Eklund, Emily J.; Pike, Robert D.; Mainkar, Anshul A.; Scheerer, Jonathan R.
Organic Letters, 2011 , vol. 13, # 5 p. 1246 - 1249
