1: pyridine / 20 °C 2: potassium tert-butylate / dimethyl sulfoxide / 5 h / 20 °C 3: methyl-magnesium iodide / diethyl ether / 0.17 h / 180 °C / |Inert atmosphere View Scheme

1: potassium tert-butylate / dimethyl sulfoxide / 5 h / 20 °C 2: methyl-magnesium iodide / diethyl ether / 0.17 h / 180 °C / |Inert atmosphere View Scheme

1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / dimethyl sulfoxide / 20 °C 2: tetrahydrofuran / 2.25 h / 0 - 20 °C 3: pyridine / 20 °C 4: potassium tert-butylate / dimethyl sulfoxide / 5 h / 20 °C 5: methyl-magnesium iodide / diethyl ether / 0.17 h / 180 °C / |Inert atmosphere View Scheme

1.1: thionyl chloride 2.1: n-butyllithium / hexane; tetrahydrofuran / 0.25 h / -78 °C 2.2: 0.75 h / -78 - 0 °C 3.1: sodium hexamethyldisilazane / tetrahydrofuran / -78 °C 3.2: 6 h / -50 °C 4.1: lithium borohydride / tetrahydrofuran / 0 °C 5.1: 1H-imidazole / dichloromethane / 20 °C 6.1: diisobutylaluminium hydride / dichloromethane; toluene / 3 h / -40 °C 7.1: triphenylphosphine; carbon tetrabromide / dichloromethane / 0.5 h / 20 °C / |Inert atmosphere 8.1: N,N,N',N,-tetramethylethylenediamine; anhydrous iron chloride / tetrahydrofuran / 0.5 h / 0 °C 9.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 3 h / 20 °C 10.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / dimethyl sulfoxide / 20 °C 11.1: tetrahydrofuran / 2.25 h / 0 - 20 °C 12.1: pyridine / 20 °C 13.1: potassium tert-butylate / dimethyl sulfoxide / 5 h / 20 °C 14.1: methyl-magnesium iodide / diethyl ether / 0.17 h / 180 °C / |Inert atmosphere View Scheme