1: 97 percent / aq. NaOH / acetonitrile; H2O / 5 h / 37 - 42 °C / α-chymotrypsin 2: 93 percent / aq. HCl / 10 h / Heating 3: 85 percent / aq. NaOH / H2O; 2-methyl-propan-2-ol / 3 h / Ambient temperature View Scheme
参考文献
Rivier, Jean E.; Jiang, Guangcheng; Porter, John; Hoeger, Carl A.; Craig, A. Grey; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 14 p. 2649 - 2662
2: 90 percent / aq. HCl / 10 h / Heating 3: 80 percent / aq. NaOH / 2-methyl-propan-2-ol; H2O / 3 h / Ambient temperature View Scheme
参考文献
Rivier, Jean E.; Jiang, Guangcheng; Porter, John; Hoeger, Carl A.; Craig, A. Grey; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 14 p. 2649 - 2662
