(S)-4-异丙基-2-恶唑烷酮合成路线 (共 117 条)
反应条件
hydrogenchloride; hydrogen; platinum(IV) oxide in ethanol; water P=75007.5 Torr;
参考文献
WO2005/49570 A1, ;
Page/Page column 10; 11 ;
反应条件
n-butyllithium in tetrahydrofuran T=-78°C; 2 h;
参考文献
Tetrahedron Asymmetry, , vol. 19, # 9 p. 1068 - 1077
反应条件
4-(N,N-dimethlyamino)pyridine in dichloromethane 1 h;
参考文献
Simon, Monika; Micle, Andreea; Badea, Valentin; Csunderlik, Carol
Synthetic Communications, 2009 , vol. 39, # 15 p. 2633 - 2639
反应条件
in methanol T=20°C; 2 h;
参考文献
Tetrahedron Letters, , vol. 44, # 18 p. 3599 - 3603
反应条件
lithium hydroxide; dihydrogen peroxide in dichloromethane
参考文献
Tetrahedron Asymmetry, , vol. 19, # 9 p. 1068 - 1077
反应条件
potassium tert-butylate in tetrahydrofuran T=0°C; 1 h; Yield given;
参考文献
Synthesis, , # 8 p. 622 - 623
反应条件
carbonic acid dimethyl ester T=50°C; 48 h;
参考文献
Kanomata, Nobuhiro; Maruyama, Satoshi; Tomono, Katsuhito; Anada, Shinnosuke
Tetrahedron Letters, 2003 , vol. 44, # 18 p. 3599 - 3603
反应条件
lithium hydroxide in tetrahydrofuran; water T=20°C; Yield given. Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 35, # 15 p. 2369 - 2372
反应条件
pyridine; selenium(IV) oxide in pyridine 1 h; Heating;
参考文献
Shafer; Molinski
Journal of Organic Chemistry, 1996 , vol. 61, # 6 p. 2044 - 2050
反应条件
1: sodium tetrahydroborate / ethanol / 24.17 h / 0 °C / Inert atmosphere; Reflux 2: potassium tert-butylate / tetrahydrofuran / 6 h / 0 °C / Inert atmosphere View Scheme
参考文献
Organic Letters, , vol. 13, # 24 p. 6576 - 6579