2-氟-4,6-二羟基苯甲醛合成路线 （共 5 条）
反应条件
boron tribromide in dichloromethane T=-78 - 20°C;
参考文献
ANACOR PHARMACEUTICALS, INC.; GLAXOSMITHKINE LLC; XIA, Yi; ALLEY, Michael, Richard Kevin; ZHOU, Yasheen; SINGH, Rajeshwar; DING, Charles; CAO, Kathy; PLATTNER, Jacob, J.; OU, Ligong; JIA, Guofeng; SARASWAT, Neerja; RAMACHANDRAN, Sreekanth; ZHOU, Ding
Patent: WO2011/17125 A1, 2011 ;
Location in patent: Page/Page column 110 ;
反应条件
trichlorophosphate in N-methyl-acetamide; water
参考文献
Rhone-Poulenc Rorer Limited
Patent: US6048893 A1, 2000 ;
US 6048893 A
Title/Abstract Full Text Show Details
Rhone-Poulenc Rorer Limited
Patent: US6124343 A1, 2000 ;
反应条件
trichlorophosphate in water
参考文献
Rhone-Poulenc Rorer Limited
Patent: US6211234 B1, 2001 ;
反应条件
1: sodium nitrite; tetrafluoroboric acid / water / 0.5 h / 20 °C 2: trichlorophosphate / 0 - 20 °C 3: boron tribromide / dichloromethane / -78 - 20 °C View Scheme
参考文献
ANACOR PHARMACEUTICALS, INC.; GLAXOSMITHKINE LLC; XIA, Yi; ALLEY, Michael, Richard Kevin; ZHOU, Yasheen; SINGH, Rajeshwar; DING, Charles; CAO, Kathy; PLATTNER, Jacob, J.; OU, Ligong; JIA, Guofeng; SARASWAT, Neerja; RAMACHANDRAN, Sreekanth; ZHOU, Ding
Patent: WO2011/17125 A1, 2011 ;
反应条件
1: trichlorophosphate / 0 - 20 °C 2: boron tribromide / dichloromethane / -78 - 20 °C View Scheme
参考文献
ANACOR PHARMACEUTICALS, INC.; GLAXOSMITHKINE LLC; XIA, Yi; ALLEY, Michael, Richard Kevin; ZHOU, Yasheen; SINGH, Rajeshwar; DING, Charles; CAO, Kathy; PLATTNER, Jacob, J.; OU, Ligong; JIA, Guofeng; SARASWAT, Neerja; RAMACHANDRAN, Sreekanth; ZHOU, Ding
Patent: WO2011/17125 A1, 2011 ;
