anhydrous tetramethylammonium chloride in methanol T=-5°C; 10 h; pH=9.5-11.0, Electrolyse;

hydrogen bromide in acetic acid T=0 - 20°C; 12 h;

1: 88 percent / n-butyllithium / tetrahydrofuran / 5.5 h / -78 °C 2: 92 percent / PdCl2(PhCN)2 / benzene / 1 h / 20 °C 3: 83 percent / sodium borohydride / ethanol / 0 - 20 °C 4: ammonium cerium(IV) nitrate / acetonitrile; H2O / 0 - 20 °C 5: 61 mg / sodium carbonate / tetrahydrofuran; H2O / 24 h / 20 °C 6: 79 percent / chromium(VI) oxide; sulfuric acid / acetone; H2O / 1.5 h / 0 - 20 °C 7: tetrabutylammonium fluoride / dimethylformamide; tetrahydrofuran / 0.17 h / 20 °C View Scheme

O-(diphenyl-phosphinyl)hydroxylamine; lithium diethylamide 1.) THF, 0 deg C, 15 min, 2.) THF, a) -70 deg C, 25 min, b) 20 deg C, 2 h; Yield given. Multistep reaction;