4-[5-(4-羟基甲基苯基)-3-(三氟甲基)-1H-吡唑-1-基]苯磺酰胺合成路线 （共 7 条）
反应条件
in ethyl acetate; acetone
反应条件
water in acetone 110 h; Reflux;
参考文献
Abdellatif, Khaled R.A.; Chowdhury, Morshed Alam; Dong, Ying; Velazquez, Carlos; Das, Dipankar; Suresh, Mavanur R.; Knaus, Edward E.
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 22 p. 9694 - 9698
反应条件
1: With N-bromosuccinmide Bromination; Irradiation; 2: Hydrolysis; 3: With sodium tetrahydroborate Reduction;
参考文献
Xenobiotica, , vol. 30, # 7 p. 731 - 744
反应条件
1: 46 percent / ethanol / 20 h / Heating 2: NBS / benzene / 3 h / Irradiation 3: H2O / acetone / 120 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 9 p. 1347 - 1365
反应条件
1: 46 percent / ethanol / 20 h / Heating 2: NBS / benzene / 3 h / Irradiation 3: H2O / acetone / 120 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 9 p. 1347 - 1365
反应条件
1: 94 percent / NaOMe / methanol / 24 h / Heating 2: 46 percent / ethanol / 20 h / Heating 3: NBS / benzene / 3 h / Irradiation 4: H2O / acetone / 120 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 40, # 9 p. 1347 - 1365
反应条件
in ethanol 24 h; Reflux;
参考文献
Boschi, Donatella; Lazzarato, Loretta; Rolando, Barbara; Filieri, Andrea; Cena, Clara; Di Stilo, Antonella; Fruttero, Roberta; Gasco, Alberto
Chemistry and Biodiversity, 2009 , vol. 6, # 3 p. 369 - 379
