(R)-2-((叔丁氧基羰基)氨基)-3-(2-甲氧基苯基)丙酸合成路线 （共 8 条）
反应条件
triethylamine in 1,4-dioxane; water 5 h; Ambient temperature;
参考文献
Danthi, Satyavijayan Narasimhan; Hill, Ronald A.
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 835 - 844
反应条件
sodium hydroxide 1.) H20, reflux, 2.) water, dioxane; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Myers, Andrew G.; Gleason, James L.; Yoon, Taeyoung; Kung, Daniel W.
Journal of the American Chemical Society, 1997 , vol. 119, # 4 p. 656 - 673
反应条件
sodium hydroxide; sodium hydrogencarbonate; lithium chloride; lithium diisopropyl amide Yield given. Multistep reaction;
参考文献
Myers, Andrew G.; Gleason, James L.; Yoon, Taeyoung
Journal of the American Chemical Society, 1995 , vol. 117, # 32 p. 8488 - 8489
反应条件
1: 80 percent / PBr3 / toluene / 0.17 h / 100 °C 2: 1.) NaOEt / 1.) EtOH, 2.) EtOH, 3 h 3: 94 percent / aq. NaOH / 6 h / Heating 5: aq. HCl / 5 h / Heating 6: 79 percent / Et3N / H2O; dioxane / 5 h / Ambient temperature View Scheme
参考文献
Danthi, Satyavijayan Narasimhan; Hill, Ronald A.
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 835 - 844
反应条件
1: 1.) NaOEt / 1.) EtOH, 2.) EtOH, 3 h 2: 94 percent / aq. NaOH / 6 h / Heating 4: aq. HCl / 5 h / Heating 5: 79 percent / Et3N / H2O; dioxane / 5 h / Ambient temperature View Scheme
参考文献
Danthi, Satyavijayan Narasimhan; Hill, Ronald A.
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 835 - 844
反应条件
1: 94 percent / aq. NaOH / 6 h / Heating 3: aq. HCl / 5 h / Heating 4: 79 percent / Et3N / H2O; dioxane / 5 h / Ambient temperature View Scheme
参考文献
Danthi, Satyavijayan Narasimhan; Hill, Ronald A.
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 835 - 844
反应条件
2: aq. HCl / 5 h / Heating 3: 79 percent / Et3N / H2O; dioxane / 5 h / Ambient temperature View Scheme
参考文献
Danthi, Satyavijayan Narasimhan; Hill, Ronald A.
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 835 - 844
反应条件
1: aq. HCl / 5 h / Heating 2: 79 percent / Et3N / H2O; dioxane / 5 h / Ambient temperature View Scheme
参考文献
Danthi, Satyavijayan Narasimhan; Hill, Ronald A.
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 3 p. 835 - 844
