4-氨基-N-甲基苯磺酰胺合成路线 （共 15 条）
反应条件
1: With ammonium thiocyanate in acetic acid T=20°C; 0.5 h; 2: With bromine in acetic acid T=20°C; 64 h; 3: With sodium hydrogencarbonate in water
参考文献
KINETEK PHARMACEUTICALS, INC.
Patent: WO2004/11460 A2, 2004 ;
Location in patent: Page 59-60 ;
WO 2004/011460 A2
反应条件
aluminum oxide; potassium hydroxide T=130°C; 0.0666667 h; microwave irradiation;
参考文献
Synthetic Communications, , vol. 38, # 18 p. 3074 - 3081
反应条件
calcium carbonate in dichloromethane; water T=0 - 20°C; P=760.051 Torr; Inert atmosphere;
参考文献
F. HOFFMANN-LA ROCHE AG; HOFFMANN-LA ROCHE INC.; BILOTTA, Joseph Anthony; CHEN, Zhi; CHIN, Elbert; DING, Qingjie; ERICKSON, Shawn David; GABRIEL, Stephen Deems; KLUMPP, Klaus; MA, Han; MERTZ, Eric; PLANCHER, Jean-Marc; WEIKERT, Robert James
Patent: WO2014/6066 A1, 2014 ;
Location in patent: Paragraph 0202 ;
反应条件
in 4-isothiocyanato0benzamide
参考文献
Agouron Pharmaceuticals Inc.
Patent: US6569878 B1, 2003 ;
US 6569878 B1
反应条件
potassium carbonate in acetone
T=0 - 30°C; 11 h;
参考文献
Wang, Gong-Bao; Wang, Lin-Fa; Li, Chao-Zhang; Sun, Jing; Zhou, Guang-Ming; Yang, Da-Cheng
Research on Chemical Intermediates, 2012 , vol. 38, # 1 p. 77 - 89
