(R)-5,5-二甲基-4-苯基-2-恶唑烷酮合成路线 （共 16 条）
反应条件
in dichloromethane 2 h; Heating;
参考文献
Oxford Asymmetry International plc
Patent: US5801249 A1, 1998 ;
反应条件
potassium tert-butylate in tetrahydrofuran T=0°C; 0.5 h;
参考文献
Bull, Steven D.; Davies, Stephen G.; Jones, Simon; Sanganee, Hitesh J.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 4 p. 387 - 398
反应条件
lithium hydroxide in tetrahydrofuran; water 1) 0 deg C, 1 h, 2) 0 deg C to room temperature;
参考文献
Davies, Stephen G.; Sanganee, Hitesh J.; Szolcsanyi, Peter
Tetrahedron, 1999 , vol. 55, # 11 p. 3337 - 3354
反应条件
potassium carbonate in ethanol 0.5 h; Heating;
参考文献
Davies, Stephen G.; Sanganee, Hitesh J.; Szolcsanyi, Peter
Tetrahedron, 1999 , vol. 55, # 11 p. 3337 - 3354
反应条件
lithium hydroxide in tetrahydrofuran; water 1) 0 deg C, 1 h, 2) 0 deg C to room temperature;
参考文献
Davies, Stephen G.; Sanganee, Hitesh J.; Szolcsanyi, Peter
Tetrahedron, 1999 , vol. 55, # 11 p. 3337 - 3354
反应条件
(R)-BTM; sodium sulfate; N-ethyl-N,N-diisopropylamine in chloroform T=20°C; 12 h;
参考文献
Journal of the American Chemical Society, , vol. 128, # 20 p. 6536 - 6537
反应条件
1: tetrahydrofuran 2: t-BuONa / tetrahydrofuran 3: i-Pr2NEt; Na2SO4; (R)-BTM / CHCl3 / 12 h / 20 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 128, # 20 p. 6536 - 6537
反应条件
diphenyl phosphoryl azide; triethylamine in toluene T=80°C; 8 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 63, # 8 p. 2742 - 2748
反应条件
1: 100 percent / SOCl2 / 2 h / Heating 2: 41 percent / diethyl ether / 3 h 3: 82 percent / CH2Cl2 / 2 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 55, # 11 p. 3337 - 3354
反应条件
1: 41 percent / diethyl ether / 3 h 2: 82 percent / CH2Cl2 / 2 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 55, # 11 p. 3337 - 3354
