2-甲基-3-氧代丁酸甲酯合成路线 （共 38 条）
参考文献
Simonis; Remmert
Chemische Berichte, 1914 , vol. 47, p. 2232
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Chakravarti
Chem. Zentralbl., 1931 , vol. 102, # II p. 1002
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Canter et al.
Journal of the Chemical Society, 1931 , p. 1255,1264
反应条件
1: H2 / Ni 2: (i) P(OPh)3, MeI, (ii) H2, Raney-Ni, MgO View Scheme
参考文献
Tai,A. et al.
Chemistry Letters, 1978 , p. 61 - 64
反应条件
sodium azide; methanesulfonic acid in ethylene glycol dimethyl ether T=-30 - 20°C; 3 h;
参考文献
Galvez, Nicanor; Moreno-Manas, Marcial; Sebastian, Rosa M.; Vallribera, Adelina
Tetrahedron, 1996 , vol. 52, # 5 p. 1609 - 1616
反应条件
hydrazine in ethanol
参考文献
Zheng, Zhaoyan; Yu, Zhengkun; Luo, Ning; Han, Xiuwen
Journal of Organic Chemistry, 2006 , vol. 71, # 26 p. 9695 - 9700
反应条件
durch Erhitzen des erhaltenen β-Phenylimino-α-methyl-buttersaeure-methylesters auf 240-260grad;
参考文献
Conrad; Limpach
Chemische Berichte, 1891 , vol. 24, p. 2991
反应条件
1: potassium tert-butylate / methanol / 23 - 60 °C 2: tetraethylammonium chloride; N,N-dimethyl-aniline; trichlorophosphate / acetonitrile / 0.33 h / 110 °C View Scheme
参考文献
Savall, Brad M.; Chavez, Frank; Tays, Kevin; Dunford, Paul J.; Cowden, Jeffery M.; Hack, Michael D.; Wolin, Ronald L.; Thurmond, Robin L.; Edwards, James P.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2429 - 2439
反应条件
phenylacetone monooxygenase from Thermobifida fusca; glucose-6-phosphate dehydrogenase; Glc 6P; NADPH in dimethyl sulfoxide T=30°C; Baeyer-Villiger oxidation; pH=9; 24 h; aq. bufferEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Rioz-Martinez, Ana; Cuetos, Anibal; Rodriguez, Cristina; De Gonzalo, Gonzalo; Lavandera, Ivan; Fraaije, Marco W.; Gotor, Vicente
Angewandte Chemie - International Edition, 2011 , vol. 50, # 36 p. 8387 - 8390
反应条件
natural kaolinitic clay in toluene
Heating;
参考文献
Ponde, Datta E.; Deshpande, Vishnu H.; Bulbule, Vivek J.; Sudalai, Ammugam; Gajare, Anil S.
Journal of Organic Chemistry, 1998 , vol. 63, # 4 p. 1058 - 1063
反应条件
oxygen; cerium(III) chloride in isopropyl alcohol
T=23°C; P=760 Torr; 16 h;
参考文献
Christoffers, Jens; Kauf, Thomas; Werner, Thomas; Roessle, Michael
European Journal of Organic Chemistry, 2006 , # 11 p. 2601 - 2608
参考文献
Tischler,S.A.; Weiler,L.
Tetrahedron Letters, 1979 , p. 4903 - 4906
