(8CI)-2-(p-甲氧基苯基)-呋喃合成路线 （共 51 条）
反应条件
sodium hydride; tri(tert-butyl)phosphine palladium complex in toluene
T=50°C; 6 h;
参考文献
Denmark, Scott E.; Baird, John D.; Regens, Christopher S.
Journal of Organic Chemistry, 2008 , vol. 73, # 4 p. 1440 - 1455
反应条件
C52H44CoN4O4; potassium hydroxide; tert-butyl alcohol
T=200°C; 1 h; Inert atmosphereDarkness; regioselective reaction;
参考文献
Qian, Ying Ying; Wong, Ka Lai; Zhang, Meng Wen; Kwok, Tsz Yiu; To, Ching Tat; Chan, Kin Shing
Tetrahedron Letters, 2012 , vol. 53, # 13 p. 1571 - 1575
反应条件
carbon monoxide; bis(dibenzylideneacetone)-palladium(0); tris(4-trifluoromethylphenyl)phosphine in methanol; dichloromethane
T=0°C; P=760 Torr; 40 h;
参考文献
Nakamura, Masaki; Yamane, Motoki; Sakurai, Hidehiro; Narasaka, Koichi
Heterocycles, 2003 , vol. 59, # 1 p. 333 - 345
反应条件
1: furan With n-butyllithium in tetrahydrofuran; hexane
T=-78 - 20°C; 0.75 h;
2: With zinc(II) chloride in tetrahydrofuran; hexane
T=0 - 20°C; 0.75 h;
3: 4-methoxyphenyl halide With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran; hexane
24 h; Reflux;
参考文献
Shinohara, Hiroyuki; Sonoda, Motohiro; Atobe, Shingo; Masuno, Haruna; Ogawa, Akiya
Tetrahedron Letters, 2011 , vol. 52, # 47 p. 6238 - 6241
反应条件
sodium methylate; tris(dibenzylideneacetone)dipalladium(0) chloroform complex; copper(l) iodide in ethylene glycol dimethyl ether; acetonitrile
T=60°C; 2 h;
参考文献
Kang, Suk-Ku; Ryu, Hyung-Chul; Son, Hoe-Joo
Synlett, 1998 , # 7 p. 771 - 773
反应条件
Pd-PEPPSI-IPent in tetrahydrofuran; toluene
T=35°C;
参考文献
Hornillos, Valentin; Giannerini, Massimo; Vila, Carlos; Fananas-Mastral, Martin; Feringa, Ben L.
Organic Letters, 2013 , vol. 15, # 19 p. 5114 - 5117
反应条件
sodium methylate; copper(l) iodide; Pd(dibenzylidene acetone)3*CHCl3 in methanol; acetonitrile
2 h; Ambient temperature;
参考文献
Kang, Suk-Ku; Ryu, Hyung-Chul; Choi, Sang-Chul
Chemical Communications, 1998 , # 12 p. 1317 - 1318
反应条件
palladium diacetate; sodium carbonate; dicyclohexyl(2',6'-diisopropoxy-[1,1'-biphenyl]-2-yl)phosphine in ethanol
T=85°C; Suzuki-Miyaura coupling; 12 h; Inert atmosphere;
参考文献
Molander, Gary A.; Canturk, Belgin; Kennedy, Lauren E.
Journal of Organic Chemistry, 2009 , vol. 74, # 3 p. 973 - 980
反应条件
potassium phosphate; palladium diacetate; 2-dicyclohexylphosphino-1,1'-biphenyl in 1-methyl-pyrrolidin-2-one
T=15 - 100°C; 24.25 h; Inert atmosphere;
参考文献
Nadres, Enrico T.; Lazareva, Anna; Daugulis, Olafs
Journal of Organic Chemistry, 2011 , vol. 76, # 2 p. 471 - 483
反应条件
tetrakis(triphenylphosphine) palladium(0) in toluene
18 h; Heating;
参考文献
Tanis, Steven P.; Deaton, Melissa V.; Dixon, Lisa A.; McMills, Mark C.; Raggon, Jeffrey W.; Collins, Mark A.
Journal of Organic Chemistry, 1998 , vol. 63, # 20 p. 6914 - 6928
