(8CI)-2-(p-甲氧基苯基)-呋喃合成路线 （共 51 条）
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in water; N,N-dimethyl-formamide
T=75 - 85°C; Suzuki coupling; Inert atmosphere;
参考文献
Haner, Jamie; Jack, Kelsey; Nagireddy, Jaipal; Raheem, Mohammed Abdul; Durham, Robin; Tam, William
Synthesis, 2011 , # 5 p. 731 - 738
反应条件
bis(acetylacetonate)nickel(II) in 1-methyl-pyrrolidin-2-one
T=70°C; Arylation; cross-coupling; 8 h;
参考文献
Kang, Suk-Ku; Ryu, Hyung-Chul; Lee, Sang-Woo
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 19 p. 2661 - 2663
反应条件
[Rh(CO)2I]2; lithium iodide in methanol
T=90°C; P=3750.38 Torr; 18 h; AutoclaveInert atmosphere;
参考文献
Dheur, Julien; Sauthier, Mathieu; Castanet, Yves; Mortreuxa, Andre
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 2-3 p. 557 - 561
反应条件
palladium diacetate; caesium carbonate; triphenylphosphine in 1-methyl-pyrrolidin-2-one
T=90°C; 1 h;
参考文献
Rao, Maddali L. N.; Awasthi, Dheeraj K.; Talode, Jalindar B.
Synlett, 2012 , vol. 23, # 13 p. 1907 - 1912
参考文献
Hashmi, A. Stephen K.; Ruppert, Thorsten L.; Knoefel, Thomas; Bats, Jan W.
Journal of Organic Chemistry, 1997 , vol. 62, # 21 p. 7295 - 7304
反应条件
1: propargyladehyde di-ethyl acetal With n-butyllithium in diethyl ether; hexane
T=20°C; 1 h;
2: 4-methoxy-benzaldehyde With titanium(IV) isopropylate; isopropylmagnesium chloride in diethyl ether; hexane
T=-40 - -35°C; 2.5 h;
3: With hydrogenchloride
Further stages.;
参考文献
Eom, Deok Ki; Choi, Seong Jib; An, Duk Keun
Heterocycles, 2007 , vol. 71, # 5 p. 1141 - 1146
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; silver(l) oxide in methanol
T=20°C; Suzuki-Miyaura cross- coupling; 1.5 h; Inert atmosphere;
参考文献
Botteselle, Giancarlo V.; Hough, Thomas L. S.; Venturoso, Raphael C.; Cella, Rodrigo; Vieira, Adriano S.; Stefani, Helio A.
Australian Journal of Chemistry, 2008 , vol. 61, # 11 p. 870 - 873
反应条件
tert.-butylnitrite; ascorbic acid powder in dimethyl sulfoxide; acetonitrile
T=20°C; 12 h; Inert atmosphereGreen chemistry; regioselective reaction;
参考文献
Crisostomo, Fernando Pinacho; Martin, Tomas; Carrillo, Romen
Angewandte Chemie - International Edition, 2014 , vol. 53, # 8 p. 2181 - 2185
Angew. Chem., 2014 , vol. 53, # 8 p. 2213 - 2217,5
反应条件
Mn(OAc)3•2H2O in ethanol
T=170°C; 0.166667 h; Microwave irradiation; regioselective reaction;
参考文献
Guchhait, Sankar K.; Kashyap, Maneesh; Saraf, Shuddham
Synthesis, 2010 , # 7 art. no. Z24009SS, p. 1166 - 1170
反应条件
1: 61 percent / MCPBA / CH2Cl2 / 20 °C
2: LiTMP / tetrahydrofuran / 20 °C
View Scheme
参考文献
Schmidt, Bernd; Wildemann, Holger
European Journal of Organic Chemistry, 2000 , # 18 p. 3145 - 3163
