3-溴-2,5-二甲基吡啶合成路线 （共 2 条）
反应条件
sulfuric acid; bromine T=155 - 175°C; 24 h;
参考文献
Zeitschrift fuer Chemie (Stuttgart, Germany), , vol. 28, # 2 p. 59 - 60
反应条件
1: With n-butyllithium in hexanes; diethyl ether T=-78°C; 1 h; Inert atmosphere; 2: With tri-isopropoxy-borane in hexanes; diethyl ether T=20°C; 3: With ammonium chloride in hexanes; diethyl ether
参考文献
NOVARTIS AG
Patent: WO2009/141386 A1, 2009 ;
Location in patent: Page/Page column 121 ;
WO 2009/141386 A1
